UniProt Q96BP3
Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (Q96BP3)
Peptidylprolyl isomerase domain and WD repeat-containing protein 1 (UniProt Q96BP3), EC 5.2.1.8: 7 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q96BP3
- Protein
- Peptidylprolyl isomerase domain and WD repeat-containing protein 1
- EC
- 5.2.1.8
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 8 · 3 records with a druggable one
Structures
8 records of Q96BP3 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2A2N | Crystal Structure of the peptidylprolyl isomerase domain of Human PPWD1 | x-ray diffraction | A, B, C | — | — |
| 2A2N | Crystal structure of the peptidylprolyl isomerase domain of human PPWD1 | x-ray diffraction | A, B, C | — | — |
| 5YZG | The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution | electron microscopy | 2 | — | — |
| 7A5P | Human C Complex Spliceosome - Medium-resolution PERIPHERY | electron microscopy | z | — | — |
| 7A5P | Human C complex spliceosome - medium-resolution periphery | electron microscopy | z | — | — |
| 8I0W | The cryo-EM structure of human C complex | electron microscopy | 3 | — | 1 (best 0.83) |
| 9FMD | Integrative model of the human post-catalytic spliceosome (P-complex) | electron microscopy | w | — | 3 (best 0.86) |
| Q96BP3 | AlphaFold monomer V2.0 prediction for peptidylprolyl isomerase domain and wd repeat-containing… | predicted | A | — | 4 (best 0.82) |
Experiment against prediction
- 2A2N chain A against the predicted model Q96BP3: TM-score 0.98, RMSD 1.06 Å
- 2A2N chain A against the predicted model Q96BP3: TM-score 0.98, RMSD 1.06 Å
- 2A2N chain C against the predicted model Q96BP3: TM-score 0.97, RMSD 0.86 Å
- 2A2N chain C against the predicted model Q96BP3: TM-score 0.97, RMSD 0.86 Å
- 9FMD chain w against the predicted model Q96BP3: TM-score 0.70, RMSD 0.64 Å
- 7A5P chain z against the predicted model Q96BP3: TM-score 0.58, RMSD 2.66 Å
- 7A5P chain z against the predicted model Q96BP3: TM-score 0.58, RMSD 2.66 Å
- 8I0W chain 3 against the predicted model Q96BP3: TM-score 0.58, RMSD 2.66 Å
- 5YZG chain 2 against the predicted model Q96BP3: TM-score 0.55, RMSD 2.83 Å
Elsewhere
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