UniProt Q96BP2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (Q96BP2)
Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 (UniProt Q96BP2): 30 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 55 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q96BP2
- Protein
- Coiled-coil-helix-coiled-coil-helix domain-containing protein 1
- Experimental structures
- 30
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 55 · 25 records with a druggable one
Structures
31 records of Q96BP2 in the MolNFT archive: 30 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J9M | Structure of the human mitochondrial ribosome (class 1) | electron microscopy | A2 | — | — |
| 6NU2 | Structural insights into unique features of the human mitochondrial ribosome recycling | electron microscopy | A2 | — | — |
| 6NU3 | Structural insights into unique features of the human mitochondrial ribosome recycling | electron microscopy | A2 | MG | 2 (best 0.83) |
| 6RW4 | Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF3 | electron microscopy | 2 | MG | 4 (best 0.85) |
| 6RW5 | Structure of human mitochondrial 28S ribosome in complex with mitochondrial IF2 and IF3 | electron microscopy | 2 | MG | 3 (best 0.86) |
| 6VLZ | Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI) | electron microscopy | A2 | MG | 1 (best 0.87) |
| 6VMI | Structure of the human mitochondrial ribosome-EF-G1 complex (ClassIII) | electron microscopy | A2 | MG | — |
| 6ZM5 | Human mitochondrial ribosome in complex with OXA1L, mRNA, A/A tRNA, P/P tRNA and nascent polypeptide | electron microscopy | A2 | MG | 1 (best 0.87) |
| 6ZM6 | Human mitochondrial ribosome in complex with mRNA, A/A tRNA and P/P tRNA | electron microscopy | A2 | MG | 2 (best 0.86) |
| 6ZS9 | Human mitochondrial ribosome in complex with ribosome recycling factor | electron microscopy | A2 | MG | — |
| 6ZSB | Human mitochondrial ribosome in complex with mRNA and P-site tRNA | electron microscopy | A2 | MG | — |
| 6ZSC | Human mitochondrial ribosome in complex with E-site tRNA | electron microscopy | A2 | MG | 1 (best 0.87) |
| 6ZSD | Human mitochondrial ribosome in complex with mRNA, P-site tRNA and E-site tRNA | electron microscopy | A2 | MG | 2 (best 0.87) |
| 6ZSG | Human mitochondrial ribosome in complex with mRNA, A-site tRNA, P-site tRNA and E-site tRNA | electron microscopy | A2 | MG | 2 (best 0.88) |
| 7A5F | Structure of the stalled human mitoribosome with P- and E-site mt-tRNAs | electron microscopy | c6 | MG | 1 (best 0.86) |
| 7A5I | Structure of the human mitoribosome with A- P-and E-site mt-tRNAs | electron microscopy | c6 | MG | 3 (best 0.88) |
| 7A5K | Structure of the human mitoribosome in the post translocation state bound to mtEF-G1 | electron microscopy | c6 | — | 2 (best 0.88) |
| 7L08 | Cryo-EM structure of the human 55S mitoribosome-RRFmt complex. | electron microscopy | A2 | MG | 1 (best 0.85) |
| 7PO1 | Initiation complex of human mitochondrial ribosome small subunit with IF3 | electron microscopy | 2 | MG | 3 (best 0.87) |
| 7PO2 | Initiation complex of human mitochondrial ribosome small subunit with IF2, fMet-tRNAMet and mRNA | electron microscopy | 2 | MG | 3 (best 0.86) |
| 7PO3 | Human mitochondrial ribosome small subunit | electron microscopy | 2 | MG | 5 (best 0.87) |
| 7QI4 | Human mitochondrial ribosome at 2.2 A resolution (bound to partly built tRNAs and mRNA) | electron microscopy | A2 | — | 2 (best 0.86) |
| 7QI6 | Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution | electron microscopy | A2 | — | 1 (best 0.86) |
| 8K2A | Cryo-EM structure of the human 55S mitoribosome with Tigecycline | electron microscopy | Sm | MG | 1 (best 0.84) |
| 8OIR | 55S human mitochondrial ribosome with mtRF1 and P-site tRNA | electron microscopy | Ac | MG | 1 (best 0.85) |
| 8OIS | 28S human mitochondrial small ribosomal subunit with mtRF1 and P-site tRNA | electron microscopy | Ac | MG | 4 (best 0.86) |
| 8QRM | mt-SSU assembly intermediate in GTPBP8 knock-out cells, state 3 | electron microscopy | 2 | — | 3 (best 0.86) |
| 8QRN | mt-SSU in GTPBP8 knock-out cells, state 4 | electron microscopy | 2 | MG | 4 (best 0.86) |
| 8XT0 | Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline | electron microscopy | Sm | — | 1 (best 0.85) |
| 8XT2 | Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline | electron microscopy | Sm | MG | 2 (best 0.88) |
| Q96BP2 | AlphaFold monomer V2.0 prediction for coiled-coil-helix-coiled-coil- helix domain-containing… | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 23 records
Experiment against prediction
- 7QI6 chain A2 against the predicted model Q96BP2: TM-score 0.95, RMSD 0.94 Å
- 8OIR chain Ac against the predicted model Q96BP2: TM-score 0.95, RMSD 0.96 Å
- 8OIS chain Ac against the predicted model Q96BP2: TM-score 0.95, RMSD 0.96 Å
- 7QI4 chain A2 against the predicted model Q96BP2: TM-score 0.95, RMSD 0.98 Å
- 6ZM6 chain A2 against the predicted model Q96BP2: TM-score 0.95, RMSD 0.98 Å
- 6ZM5 chain A2 against the predicted model Q96BP2: TM-score 0.94, RMSD 0.99 Å
- 7PO2 chain 2 against the predicted model Q96BP2: TM-score 0.94, RMSD 0.95 Å
- 7PO3 chain 2 against the predicted model Q96BP2: TM-score 0.94, RMSD 1.06 Å
- 8K2A chain Sm against the predicted model Q96BP2: TM-score 0.94, RMSD 1.09 Å
- 3J9M chain A2 against the predicted model Q96BP2: TM-score 0.94, RMSD 1.10 Å
Elsewhere
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