UniProt Q96B36
Proline-rich AKT1 substrate 1 (Q96B36)
Proline-rich AKT1 substrate 1 (UniProt Q96B36): 7 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96B36
- Protein
- Proline-rich AKT1 substrate 1
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
8 records of Q96B36 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5WBL | Crystal structure of the Arabidopsis thaliana Raptor in complex with the TOS peptide of human PRAS40 | x-ray diffraction | T | — | 2 (best 0.65) |
| 5WBL | Crystal structure of the arabidopsis thaliana raptor in complex with the tos peptide of human PRAS40 | x-ray diffraction | T | — | — |
| 5WBU | Crystal structure of mTOR(deltaN)-mLST8-PRAS40(alpha-helix & beta-strand) complex | x-ray diffraction | P, R, O, Q | — | — |
| 5WBU | Crystal structure of MTOR(DELTAN)-MLST8-PRAS40(ALPHA-helix & beta- strand) complex | x-ray diffraction | P, R, O, Q | — | — |
| 5WBY | Crystal structure of mTOR(deltaN)-mLST8-PRAS40(beta-strand) complex | x-ray diffraction | P, O | — | — |
| 5WBY | Crystal structure of MTOR(DELTAN)-MLST8-PRAS40(BETA-strand) complex | x-ray diffraction | P, O | — | — |
| 6SB0 | Cryo-EM structure of MTORC1 bound to PRAS40-fused active RAGA/C gtpases | electron microscopy | T, O | — | — |
| Q96B36 | AlphaFold monomer V2.0 prediction for proline-rich AKT1 substrate 1 (Q96B36) | predicted | A | — | — |
Experiment against prediction
- 5WBU chain R against the predicted model Q96B36: TM-score 0.67, RMSD 0.58 Å
- 5WBU chain R against the predicted model Q96B36: TM-score 0.67, RMSD 0.58 Å
- 5WBU chain Q against the predicted model Q96B36: TM-score 0.66, RMSD 0.58 Å
- 5WBU chain Q against the predicted model Q96B36: TM-score 0.66, RMSD 0.58 Å
- 6SB0 chain T against the predicted model Q96B36: TM-score 0.49, RMSD 1.18 Å
- 6SB0 chain O against the predicted model Q96B36: TM-score 0.49, RMSD 1.18 Å
- 5WBL chain T against the predicted model Q96B36: TM-score 0.41, RMSD 0.86 Å
- 5WBL chain T against the predicted model Q96B36: TM-score 0.41, RMSD 0.86 Å
- 5WBU chain P against the predicted model Q96B36: TM-score 0.37, RMSD 1.21 Å
- 5WBU chain P against the predicted model Q96B36: TM-score 0.37, RMSD 1.21 Å
Elsewhere
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