UniProt Q96B26
Exosome complex component RRP43 (Q96B26)
Exosome complex component RRP43 (UniProt Q96B26): 10 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96B26
- Protein
- Exosome complex component RRP43
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 5 · 2 records with a druggable one
Structures
11 records of Q96B26 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2NN6 | Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4… | x-ray diffraction | C | — | — |
| 2NN6 | Structure of the human RNA exosome composed of RRP41, RRP45, RRP46, RRP43, MTR3, RRP42, CSL4, RRP4… | x-ray diffraction | C | — | — |
| 6D6Q | Human nuclear exosome-MTR4 RNA complex - overall reconstruction | electron microscopy | C | — | 4 (best 0.82) |
| 6D6Q | Human nuclear exosome-MTR4 RNA complex - overall reconstruction | electron microscopy | C | — | — |
| 6D6R | Human nuclear exosome-MTR4 RNA complex - composite MAP after focused reconstruction | electron microscopy | C | — | — |
| 6H25 | Human nuclear RNA exosome EXO-10-MPP6 complex | electron microscopy | C | — | — |
| 6H25 | Human nuclear RNA exosome exo-10-MPP6 complex | electron microscopy | C | — | — |
| 9G8M | human 80S ribosome bound by a SKI2-exosome complex | electron microscopy | N | — | — |
| 9G8N | 80S-bound human Ski2-exosome complex | electron microscopy | N | — | 1 (best 0.71) |
| 9G8O | human 40S ribosome bound by a SKI238-exosome complex | electron microscopy | L | — | — |
| Q96B26 | AlphaFold monomer V2.0 prediction for exosome complex component RRP43 (Q96B26) | predicted | A | — | — |
Experiment against prediction
- 6D6R chain C against the predicted model Q96B26: TM-score 0.98, RMSD 0.76 Å
- 6D6Q chain C against the predicted model Q96B26: TM-score 0.98, RMSD 0.78 Å
- 6D6Q chain C against the predicted model Q96B26: TM-score 0.98, RMSD 0.78 Å
- 6H25 chain C against the predicted model Q96B26: TM-score 0.97, RMSD 0.95 Å
- 6H25 chain C against the predicted model Q96B26: TM-score 0.97, RMSD 0.95 Å
- 9G8N chain N against the predicted model Q96B26: TM-score 0.97, RMSD 1.13 Å
- 9G8O chain L against the predicted model Q96B26: TM-score 0.97, RMSD 1.17 Å
- 9G8M chain N against the predicted model Q96B26: TM-score 0.96, RMSD 1.20 Å
- 2NN6 chain C against the predicted model Q96B26: TM-score 0.96, RMSD 1.30 Å
- 2NN6 chain C against the predicted model Q96B26: TM-score 0.96, RMSD 1.30 Å
Elsewhere
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