UniProt Q96A44
SPRY domain-containing SOCS box protein 4 (Q96A44)
SPRY domain-containing SOCS box protein 4 (UniProt Q96A44): 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q96A44
- Protein
- SPRY domain-containing SOCS box protein 4
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 5 · 1 record with a druggable one
Structures
7 records of Q96A44 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2V24 | Structure of the human SPRY domain-containing SOCS box protein SSB-4 | x-ray diffraction | A | — | — |
| 2V24 | Structure of the human spry domain-containing socs box protein ssb-4 | x-ray diffraction | A | — | — |
| 6DN7 | SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) Cyclic peptide inhibitor | x-ray diffraction | A, C | CL | — |
| 6DN7 | Spry domain-containing socs box protein 2 complexed with WDINNN(BAL) cyclic peptide inhibitor | x-ray diffraction | A, C | CL | — |
| 6DN8 | SPRY domain-containing SOCS box protein 2 complexed with (GZJ)VDINNN(CY3) Cyclic peptide inhibitor | x-ray diffraction | A, C, E | SO4 | 3 (best 0.75) |
| 6DN8 | Spry domain-containing socs box protein 2 complexed with (gzj) VDINNN(CY3) cyclic peptide inhibitor | x-ray diffraction | A, C, E | SO4 | — |
| Q96A44 | AlphaFold monomer V2.0 prediction for spry domain-containing socs box protein 4 (Q96A44) | predicted | A | — | 2 (best 0.32) |
Ligands
Experiment against prediction
- 6DN7 chain C against the predicted model Q96A44: TM-score 1.00, RMSD 0.29 Å
- 6DN7 chain C against the predicted model Q96A44: TM-score 1.00, RMSD 0.29 Å
- 6DN8 chain A against the predicted model Q96A44: TM-score 1.00, RMSD 0.31 Å
- 6DN8 chain A against the predicted model Q96A44: TM-score 1.00, RMSD 0.31 Å
- 6DN8 chain E against the predicted model Q96A44: TM-score 1.00, RMSD 0.35 Å
- 6DN8 chain E against the predicted model Q96A44: TM-score 1.00, RMSD 0.35 Å
- 6DN7 chain A against the predicted model Q96A44: TM-score 1.00, RMSD 0.37 Å
- 6DN7 chain A against the predicted model Q96A44: TM-score 1.00, RMSD 0.37 Å
- 6DN8 chain C against the predicted model Q96A44: TM-score 0.99, RMSD 0.57 Å
- 6DN8 chain C against the predicted model Q96A44: TM-score 0.99, RMSD 0.57 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.