UniProt Q969V5
Mitochondrial ubiquitin ligase activator of NFKB 1 (Q969V5)
Mitochondrial ubiquitin ligase activator of NFKB 1 (UniProt Q969V5), EC 2.3.2.27: 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound. Binding sites, druggability and experiment against prediction…
- UniProt
- Q969V5
- Protein
- Mitochondrial ubiquitin ligase activator of NFKB 1
- EC
- 2.3.2.27
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 2
Structures
6 records of Q969V5 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6K2K | Solution structure of MUL1-RING domain | solution nmr | A | ZN | — |
| 6K2K | Solution structure of MUL1-ring domain | solution nmr | A | ZN | — |
| 6M2C | Distinct mechanism of MUL1-RING domain simultaneously recruiting E2 enzyme and the substrate… | x-ray diffraction | E, F, G, H | ZN | — |
| 6M2C | Distinct mechanism of MUL1-ring domain simultaneously recruiting E2 enzyme and the substrate… | x-ray diffraction | E, F, G, H | ZN | — |
| 6M2D | MUL1-ring domain | x-ray diffraction | A, B, C, D, E, F | ZN, SO4 | — |
| Q969V5 | AlphaFold monomer V2.0 prediction for mitochondrial ubiquitin ligase activator of nfkb 1 (Q969V5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6M2D chain D against the predicted model Q969V5: TM-score 0.92, RMSD 1.10 Å
- 6M2C chain E against the predicted model Q969V5: TM-score 0.92, RMSD 1.26 Å
- 6M2C chain E against the predicted model Q969V5: TM-score 0.92, RMSD 1.26 Å
- 6M2D chain A against the predicted model Q969V5: TM-score 0.89, RMSD 1.30 Å
- 6K2K chain A against the predicted model Q969V5: TM-score 0.75, RMSD 1.93 Å
- 6K2K chain A against the predicted model Q969V5: TM-score 0.75, RMSD 1.93 Å
Elsewhere
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