UniProt Q95PM0
Cysteine protease (Q95PM0)
Cysteine protease (UniProt Q95PM0), EC 3.4.22.15: 12 experimental structures on GenesisL1, 3 ligands bound, 18 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q95PM0
- Protein
- Cysteine protease
- EC
- 3.4.22.15
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 18 · 4 records with a druggable one
Structures
12 records of Q95PM0 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2P7U | The crystal structure of rhodesain, the major cysteine protease of T. brucei rhodesiense, bound to… | x-ray diffraction | A | — | — |
| 2P7U | The crystal structure of rhodesain, the major cysteine protease of T. brucei rhodesiense, bound to… | x-ray diffraction | A | — | — |
| 2P86 | The high resolution crystal structure of rhodesain, the major cathepsin L protease from T. brucei… | x-ray diffraction | A | — | — |
| 2P86 | The high resolution crystal structure of rhodesain, the major cathepsin L protease from T. brucei… | x-ray diffraction | A | — | — |
| 6EX8 | Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor | x-ray diffraction | A, B | C2K | 5 (best 0.78) |
| 6EX8 | Crystal structure of rhodesain in complex with a macrolactam inhibitor | x-ray diffraction | A, B | — | — |
| 6EXO | Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor | x-ray diffraction | A, B | C3E | 6 (best 0.78) |
| 6EXO | Crystal structure of rhodesain in complex with a macrolactam inhibitor | x-ray diffraction | A, B | — | — |
| 6EXQ | Crystal Structure of Rhodesain in complex with a Macrolactam Inhibitor | x-ray diffraction | A, B | C2W | 4 (best 0.75) |
| 6EXQ | Crystal structure of rhodesain in complex with a macrolactam inhibitor | x-ray diffraction | A, B | — | — |
| 7AVM | Crystal Structure of Pro-Rhodesain C150A | x-ray diffraction | A | — | 3 (best 0.58) |
| 7AVM | Crystal structure of pro-rhodesain C150A | x-ray diffraction | A | — | — |
Ligands
- C2K · (3~{S})-~{N}-[1-(aminomethyl)cyclopropyl]-19-chloranyl-5-oxidanylidene-9-(trifluoromethyl)-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(20),6(11),7,9,18,21-hexaene-3-carboxamide · in 1 record
- C2W · (3~{S})-19-chloranyl-~{N}-(1-cyanocyclopropyl)-8-methoxy-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(20),6(11),7,9,18,21-hexaene-3-carboxamide · in 1 record
- C3E · (3~{S},14~{E})-19-chloranyl-~{N}-(1-cyanocyclopropyl)-5-oxidanylidene-12,17-dioxa-4-azatricyclo[16.2.2.0^{6,11}]docosa-1(21),6(11),7,9,14,18(22),19-heptaene-3-carboxamide · in 1 record
Elsewhere
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