UniProt Q94519

Acyl carrier protein, mitochondrial (Q94519)

Acyl carrier protein, mitochondrial (UniProt Q94519): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q94519
Protein: Acyl carrier protein, mitochondrial
Experimental structures: 4
Predicted models: 1
Ligands: 2
Pockets: 10 · 4 records with a druggable one

Structures

5 records of Q94519 in the MolNFT archive: 4 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
8B9Z	Drosophila melanogaster complex I in the Active state (Dm1)	electron microscopy	T, U	EHZ	3 (best 0.86)
8BA0	Drosophila melanogaster complex I in the Twisted state (Dm2)	electron microscopy	T, U	EHZ	3 (best 0.86)
8ESW	Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1	electron microscopy	AC, AB	ZMP	3 (best 0.88)
8ESZ	Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state	electron microscopy	AC, AB	ZMP	1 (best 0.86)
Q94519	AlphaFold monomer V2.0 prediction for acyl carrier protein, mitochondrial (Q94519)	predicted	A	—	—

Ligands

EHZ · ~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate · in 2 records
ZMP · S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy) butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate · in 2 records

Experiment against prediction

8ESW chain AC against the predicted model Q94519: TM-score 0.97, RMSD 0.63 Å
8B9Z chain U against the predicted model Q94519: TM-score 0.96, RMSD 0.72 Å
8ESZ chain AC against the predicted model Q94519: TM-score 0.96, RMSD 0.75 Å
8ESZ chain AB against the predicted model Q94519: TM-score 0.95, RMSD 0.79 Å
8ESW chain AB against the predicted model Q94519: TM-score 0.93, RMSD 0.90 Å
8B9Z chain T against the predicted model Q94519: TM-score 0.92, RMSD 1.06 Å
8BA0 chain U against the predicted model Q94519: TM-score 0.91, RMSD 1.21 Å
8BA0 chain T against the predicted model Q94519: TM-score 0.91, RMSD 1.25 Å

Elsewhere

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