UniProt Q94511
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (Q94511)
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (UniProt Q94511), EC 7.1.1.2: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 17 pockets. Binding sites, druggability and experiment…
- UniProt
- Q94511
- Protein
- NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
- EC
- 7.1.1.2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 17 · 5 records with a druggable one
Structures
5 records of Q94511 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8B9Z | Drosophila melanogaster complex I in the Active state (Dm1) | electron microscopy | G | SF4, FES, NA | 2 (best 0.88) |
| 8BA0 | Drosophila melanogaster complex I in the Twisted state (Dm2) | electron microscopy | G | SF4, FES | 1 (best 0.90) |
| 8ESW | Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1 | electron microscopy | S1 | SF4, FES | 4 (best 0.88) |
| 8ESZ | Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state | electron microscopy | S1 | SF4, FES | 4 (best 0.88) |
| Q94511 | AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase 75 kda subunit, mitochondrial… | predicted | A | — | 6 (best 0.59) |
Ligands
Experiment against prediction
- 8B9Z chain G against the predicted model Q94511: TM-score 0.99, RMSD 0.83 Å
- 8ESZ chain S1 against the predicted model Q94511: TM-score 0.99, RMSD 0.87 Å
- 8ESW chain S1 against the predicted model Q94511: TM-score 0.99, RMSD 0.90 Å
- 8BA0 chain G against the predicted model Q94511: TM-score 0.99, RMSD 0.96 Å
Elsewhere
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