UniProt Q93ZG9
Peptidyl-prolyl cis-trans isomerase FKBP53 (Q93ZG9)
Peptidyl-prolyl cis-trans isomerase FKBP53 (UniProt Q93ZG9), EC 5.2.1.8: 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 13 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q93ZG9
- Protein
- Peptidyl-prolyl cis-trans isomerase FKBP53
- EC
- 5.2.1.8
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 13 · 2 records with a druggable one
Structures
7 records of Q93ZG9 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6J2M | Crystal structure of AtFKBP53 C-terminal domain | x-ray diffraction | A | FK5, CL | 1 (best 0.34) |
| 6J2M | Crystal structure of ATFKBP53 C-terminal domain | x-ray diffraction | A | FK5, CL | — |
| 6J2Z | AtFKBP53 N-terminal Nucleoplasmin Domain | x-ray diffraction | F, G, H, I, J, A, B, C, D, E | — | 11 (best 0.82) |
| 6J2Z | ATFKBP53 N-terminal nucleoplasmin domain | x-ray diffraction | F, G, H, I, J, A, B, C, D, E | — | — |
| 7F2J | Crystal structure of AtFKBP53 FKBD in complex with rapamycin | x-ray diffraction | A, B | RAP, SO4 | 1 (best 0.65) |
| 7F2J | Crystal structure of ATFKBP53 fkbd in complex with rapamycin | x-ray diffraction | A, B | RAP, SO4 | — |
| Q93ZG9 | AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase FKBP53 (Q93ZG9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6J2M chain A against the predicted model Q93ZG9: TM-score 0.97, RMSD 0.94 Å
- 6J2M chain A against the predicted model Q93ZG9: TM-score 0.97, RMSD 0.94 Å
- 7F2J chain B against the predicted model Q93ZG9: TM-score 0.96, RMSD 0.75 Å
- 7F2J chain B against the predicted model Q93ZG9: TM-score 0.96, RMSD 0.75 Å
- 7F2J chain A against the predicted model Q93ZG9: TM-score 0.96, RMSD 0.95 Å
- 7F2J chain A against the predicted model Q93ZG9: TM-score 0.96, RMSD 0.95 Å
- 6J2Z chain F against the predicted model Q93ZG9: TM-score 0.94, RMSD 0.93 Å
- 6J2Z chain F against the predicted model Q93ZG9: TM-score 0.94, RMSD 0.93 Å
- 6J2Z chain D against the predicted model Q93ZG9: TM-score 0.93, RMSD 1.02 Å
- 6J2Z chain D against the predicted model Q93ZG9: TM-score 0.93, RMSD 1.02 Å
Elsewhere
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