UniProt Q93LQ9
Serine Beta-Lactamase KPC-2 (Q93LQ9)
Serine Beta-Lactamase KPC-2 (UniProt Q93LQ9), EC 3.5.2.6: 20 experimental structures on GenesisL1, 8 ligands bound, 89 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q93LQ9
- Protein
- Serine Beta-Lactamase KPC-2
- EC
- 3.5.2.6
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 89 · 12 records with a druggable one
Structures
20 records of Q93LQ9 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2OV5 | Crystal structure of the KPC-2 carbapenemase | x-ray diffraction | A, B, C | BCN | 6 (best 0.64) |
| 2OV5 | Crystal structure of the kpc-2 carbapenemase | x-ray diffraction | A, B, C | BCN | 6 (best 0.64) |
| 3E2K | Crystal Structure of the KPC-2 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) | x-ray diffraction | A, B | — | 6 (best 0.76) |
| 3E2K | Crystal structure of the kpc-2 beta-LACTAMASE/BETA-lactamase inhibitor protein (blip) | x-ray diffraction | A, B | — | 6 (best 0.76) |
| 3E2L | Crystal Structure of the KPC-2 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) | x-ray diffraction | A, B | — | 5 (best 0.70) |
| 3E2L | Crystal structure of the kpc-2 beta-LACTAMASE/BETA-lactamase inhibitor protein (blip) | x-ray diffraction | A, B | — | 5 (best 0.70) |
| 6J8Q | Serine Beta-Lactamase KPC-2 in Complex with Dual MBL/SBL Inhibitor WL-001 | x-ray diffraction | A, B, C, D | BHU, SO4 | 10 (best 0.65) |
| 6J8Q | Serine beta-lactamase kpc-2 in complex with dual MBL/SBL inhibitor wl- 001 | x-ray diffraction | A, B, C, D | BHU, SO4 | — |
| 6JN3 | Serine Beta-Lactamase KPC-2 in Complex with Dual MBL/SBL Inhibitor MS05 | x-ray diffraction | A, B, C, D | BX6 | 10 (best 0.73) |
| 6JN3 | Serine beta-lactamase kpc-2 in complex with dual MBL/SBL inhibitor MS05 | x-ray diffraction | A, B, C, D | BX6 | — |
| 6JN4 | Serine Beta-Lactamase KPC-2 in Complex with Dual MBL/SBL Inhibitor WL-001 | x-ray diffraction | A, B, C, D | BX9 | 11 (best 0.75) |
| 6JN4 | Serine beta-lactamase kpc-2 in complex with dual MBL/SBL inhibitor wl- 001 | x-ray diffraction | A, B, C, D | BX9 | — |
| 6JN5 | Serine Beta-Lactamase KPC-2 in Complex with Dual MBL/SBL Inhibitor MS23 | x-ray diffraction | A, B, C, D | BXU | 11 (best 0.78) |
| 6JN5 | Serine beta-lactamase kpc-2 in complex with dual MBL/SBL inhibitor MS23 | x-ray diffraction | A, B, C, D | BXU | — |
| 7E9A | Crystal structure of KPC-2 in complex with (S)-2-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-3-yl)ac… | x-ray diffraction | A, B, C, D | J00 | 8 (best 0.75) |
| 7E9A | Crystal structure of kpc-2 in complex with (S)-2-(1-hydroxy-1,3… | x-ray diffraction | A, B, C, D | J00 | — |
| 7LJK | Crystal structure of the deacylation deficient KPC-2 F72Y mutant | x-ray diffraction | A, B | — | 2 (best 0.36) |
| 7LJK | Crystal structure of the deacylation deficient kpc-2 F72Y mutant | x-ray diffraction | A, B | — | — |
| 7LK8 | Crystal structure of KPC-2 T215P mutant | x-ray diffraction | A, B | NA | 3 (best 0.64) |
| 7LK8 | Crystal structure of kpc-2 T215P mutant | x-ray diffraction | A, B | NA | — |
Ligands
- BCN · Bicine · in 2 records
- BHU · [[(2S)-2-methyl-3-sulfanyl-propanoyl]amino]methylboronic acid · in 2 records
- BX6 · [(1R)-1-[[(2S)-2-methyl-3-sulfanyl-propanoyl]amino]-2-phenyl-ethyl]boronic acid · in 2 records
- BX9 · [(R)-(4-fluorophenyl)-[[(2S)-2-methyl-3-sulfanyl-propanoyl]amino]methyl]boronic acid · in 2 records
- BXU · [(S)-(4-fluorophenyl)-[[(2S)-2-methyl-3-sulfanyl-propanoyl]amino]methyl]boronic acid · in 2 records
- J00 · 2-[(3S)-1-oxidanyl-3H-2,1-benzoxaborol-3-yl]prop-2-enoic acid · in 2 records
- NA · Sodium ion · in 2 records
- SO4 · Sulfate ion · in 2 records
Elsewhere
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