UniProt Q92997
Segment polarity protein dishevelled homolog DVL-3 (Q92997)
Segment polarity protein dishevelled homolog DVL-3 (UniProt Q92997): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 1 pocket. Binding sites, druggability and experiment against prediction…
- UniProt
- Q92997
- Protein
- Segment polarity protein dishevelled homolog DVL-3
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 1 · 0 records with a druggable one
Structures
4 records of Q92997 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ZC6 | Small-molecule inhibitors of the PDZ domain of dishevelled proteins interrupt wnt signalling | x-ray diffraction | A | QEN | — |
| 6ZC8 | Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling | x-ray diffraction | A, B | QEK | 1 (best 0.30) |
| 6ZC8 | Small-molecule inhibitors of the PDZ domain of dishevelled proteins interrupt wnt signalling | x-ray diffraction | A, B | QEK | — |
| Q92997 | AlphaFold monomer V2.0 prediction for segment polarity protein dishevelled homolog dvl-3 (Q92997) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6ZC8 chain B against the predicted model Q92997: TM-score 0.90, RMSD 1.17 Å
- 6ZC8 chain B against the predicted model Q92997: TM-score 0.90, RMSD 1.17 Å
- 6ZC6 chain A against the predicted model Q92997: TM-score 0.88, RMSD 1.79 Å
- 6ZC8 chain A against the predicted model Q92997: TM-score 0.88, RMSD 1.97 Å
- 6ZC8 chain A against the predicted model Q92997: TM-score 0.88, RMSD 1.97 Å
Elsewhere
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