UniProt Q92833
Protein Jumonji (Q92833)
Protein Jumonji (UniProt Q92833): 9 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q92833
- Protein
- Protein Jumonji
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 3 · 2 records with a druggable one
Structures
10 records of Q92833 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6C23 | Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the Compact Active State | electron microscopy | E, B | — | — |
| 6C23 | Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the compact active state | electron microscopy | E, B | — | — |
| 6C24 | Cryo-EM structure of PRC2 bound to cofactors AEBP2 and JARID2 in the extended active state | electron microscopy | B, E | — | — |
| 6NQ3 | Crystal Structure of a SUZ12-RBBP4-PHF19-JARID2 Heterotetrameric Complex | x-ray diffraction | D, H | — | — |
| 6NQ3 | Crystal structure of a SUZ12-RBBP4-PHF19-JARID2 heterotetrameric complex | x-ray diffraction | D, H | — | — |
| 6WKR | PRC2-AEBP2-JARID2 bound to H2AK119UB1 nucleosome | electron microscopy | B, E | — | — |
| 7KSO | Cryo-EM structure of PRC2:EZH1-AEBP2-JARID2 | electron microscopy | F | — | — |
| 8TB9 | PRC2-J119-450 monomer bound to H1-nucleosome | electron microscopy | B | — | 2 (best 0.85) |
| 9C8U | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min | electron microscopy | E | — | 1 (best 0.75) |
| Q92833 | AlphaFold monomer V2.0 prediction for protein jumonji (Q92833) | predicted | A | — | — |
Experiment against prediction
- 6C24 chain B against the predicted model Q92833: TM-score 0.60, RMSD 0.65 Å
- 9C8U chain E against the predicted model Q92833: TM-score 0.56, RMSD 1.43 Å
- 6NQ3 chain D against the predicted model Q92833: TM-score 0.55, RMSD 0.28 Å
- 6NQ3 chain D against the predicted model Q92833: TM-score 0.55, RMSD 0.28 Å
- 6C24 chain E against the predicted model Q92833: TM-score 0.45, RMSD 2.11 Å
- 6WKR chain E against the predicted model Q92833: TM-score 0.43, RMSD 2.32 Å
- 8TB9 chain B against the predicted model Q92833: TM-score 0.43, RMSD 2.09 Å
- 6WKR chain B against the predicted model Q92833: TM-score 0.41, RMSD 2.64 Å
- 6C23 chain E against the predicted model Q92833: TM-score 0.41, RMSD 1.57 Å
- 6C23 chain E against the predicted model Q92833: TM-score 0.41, RMSD 1.57 Å
Elsewhere
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