UniProt Q92794
Histone acetyltransferase KAT6A (Q92794)
Histone acetyltransferase KAT6A (UniProt Q92794), EC 2.3.1.48: 33 experimental structures on GenesisL1, 5 ligands bound, 21 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q92794
- Protein
- Histone acetyltransferase KAT6A
- EC
- 2.3.1.48
- Experimental structures
- 33
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 21 · 4 records with a druggable one
Structures
33 records of Q92794 in the MolNFT archive: 33 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1M36 | Solution Structure of a CCHC Zinc Finger from MOZ | solution nmr | A | — | — |
| 1M36 | Solution structure of a cchc zinc finger from moz | solution nmr | A | — | — |
| 2LN0 | Structure of MOZ | solution nmr | A | — | — |
| 2LN0 | Structure of moz | solution nmr | A | — | — |
| 2OZU | Crystal structure of human MYST histone acetyltransferase 3 in complex with acetylcoenzyme A | x-ray diffraction | A | — | — |
| 2OZU | Crystal structure of human myst histone acetyltransferase 3 in complex with acetylcoenzyme a | x-ray diffraction | A | — | — |
| 2RC4 | Crystal Structure of the HAT domain of the human MOZ protein | x-ray diffraction | A | — | — |
| 2RC4 | Crystal structure of the hat domain of the human moz protein | x-ray diffraction | A | — | — |
| 3V43 | Crystal structure of MOZ | x-ray diffraction | A | — | — |
| 3V43 | Crystal structure of moz | x-ray diffraction | A | — | — |
| 4LJN | Crystal Structure of MOZ double PHD finger | x-ray diffraction | A | — | — |
| 4LJN | Crystal structure of moz double phd finger | x-ray diffraction | A | — | — |
| 4LK9 | Crystal Structure of MOZ double PHD finger histone H3 tail complex | x-ray diffraction | A | — | — |
| 4LK9 | Crystal structure of moz double phd finger histone H3 tail complex | x-ray diffraction | A | — | — |
| 4LKA | Crystal Structure of MOZ double PHD finger histone H3K9ac complex | x-ray diffraction | A | — | — |
| 4LKA | Crystal structure of moz double phd finger histone H3K9AC complex | x-ray diffraction | A | — | — |
| 4LLB | Crystal Structure of MOZ double PHD finger histone H3K14ac complex | x-ray diffraction | A, B | — | — |
| 4LLB | Crystal structure of moz double phd finger histone H3K14AC complex | x-ray diffraction | A, B | — | — |
| 5B75 | Crystal structure of MOZ double PHD finger in complex with histone H3 butyrylation at K14 | x-ray diffraction | A | — | — |
| 5B75 | Crystal structure of moz double phd finger in complex with histone H3 butyrylation at K14 | x-ray diffraction | A | — | — |
| 5B76 | Crystal structure of MOZ double PHD finger domain in complex with histone H3 crotonylation at K14 | x-ray diffraction | A | — | — |
| 5B76 | Crystal structure of moz double phd finger domain in complex with histone H3 crotonylation at K14 | x-ray diffraction | A | — | — |
| 5B77 | Crystal structrue of MOZ double PHD finger in complex with histone H3 propionylation at K14 | x-ray diffraction | A | ZN, SO4 | — |
| 5B77 | Crystal structrue of moz double phd finger in complex with histone H3 propionylation at K14 | x-ray diffraction | A | — | — |
| 5B78 | Crystal structure of MOZ double PHD finger mutant-S210D/N235R in complex with histone H3… | x-ray diffraction | A | ZN | 1 (best 0.42) |
| 5B78 | Crystal structure of moz double phd finger mutant-S210D/N235R in complex with histone H3… | x-ray diffraction | A | — | — |
| 6LSB | Crystal Structure of DPF domain of MOZ in complex with H3K14bz peptide | x-ray diffraction | A | ZN | — |
| 6LSB | Crystal structure of dpf domain of moz in complex with H3K14BZ peptide | x-ray diffraction | A | ZN | — |
| 7Y43 | Crystal structure of the KAT6A WH domain and its bound double stranded DNA | x-ray diffraction | A | MG | 1 (best 0.55) |
| 8DD5 | Crystal structure of KAT6A in complex with inhibitor CTx-648 (PF-9363) | x-ray diffraction | A | R7L, ZN | 4 (best 0.60) |
| 8H7A | Crystal structure of the dimer form KAT6A WH domain with its bound double stranded DNA | x-ray diffraction | A, B, E, F | — | 2 (best 0.73) |
| 9FKR | KAT6A in complex with small molecule inhibitor bay-184 | x-ray diffraction | A, B | ZN, A1IDR | 13 (best 0.68) |
| Q92794 | AlphaFold monomer V2.0 prediction for histone acetyltransferase KAT6A (Q92794) | — | — | — |
Ligands
- ZN · Zinc ion · in 6 records
- A1IDR · 6-(dimethylamino)-~{N}-(2-phenylphenyl)sulfonyl-1-benzofuran-2-carboxamide · in 1 record
- MG · Magnesium ion · in 1 record
- R7L · 2,6-dimethoxy-N-{4-methoxy-6-[(1H-pyrazol-1-yl)methyl]-1,2-benzoxazol-3-yl}benzene-1-sulfonamide · in 1 record
- SO4 · Sulfate ion · in 1 record
Elsewhere
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