UniProt Q92692
Nectin-2 (Q92692)
Nectin-2 (UniProt Q92692): 11 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q92692
- Protein
- Nectin-2
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 4 · 0 records with a druggable one
Structures
12 records of Q92692 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3R0N | Crystal Structure of the Immunoglobulin variable domain of Nectin-2 | x-ray diffraction | A | — | — |
| 3R0N | Crystal structure of the immunoglobulin variable domain of nectin-2 | x-ray diffraction | A | — | — |
| 4DFH | Crystal structure of cell adhesion molecule nectin-2/CD112 variable domain | x-ray diffraction | A, B | — | — |
| 4DFH | Crystal structure of cell adhesion molecule nectin-2/CD112 variable domain | x-ray diffraction | A, B | — | — |
| 4DFI | Crystal structure of cell adhesion molecule nectin-2/CD112 mutant FAMP | x-ray diffraction | A | — | — |
| 4DFI | Crystal structure of cell adhesion molecule nectin-2/CD112 mutant famp | x-ray diffraction | A | — | — |
| 4HZA | Crystal Structure of the Immunoglobulin variable domain of Nectin-2 in monoclinic form | x-ray diffraction | A, B | — | — |
| 4HZA | Crystal structure of the immunoglobulin variable domain of nectin-2 in monoclinic form | x-ray diffraction | A, B | — | — |
| 5V52 | Structure of TIGIT bound to nectin-2 (CD112) | x-ray diffraction | C, D | NAG | 3 (best 0.40) |
| 5V52 | Structure of tigit bound to nectin-2 (CD112) | x-ray diffraction | C, D | NAG | — |
| 8X6B | Crystal structure of immune receptor PVRIG in complex with ligand Nectin-2 | x-ray diffraction | A | — | 1 (best 0.35) |
| Q92692 | AlphaFold monomer V2.0 prediction for nectin-2 (Q92692) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 4DFH chain B against the predicted model Q92692: TM-score 0.95, RMSD 1.28 Å
- 4DFH chain B against the predicted model Q92692: TM-score 0.95, RMSD 1.28 Å
- 4HZA chain A against the predicted model Q92692: TM-score 0.95, RMSD 1.46 Å
- 4HZA chain A against the predicted model Q92692: TM-score 0.95, RMSD 1.46 Å
- 5V52 chain C against the predicted model Q92692: TM-score 0.95, RMSD 1.43 Å
- 5V52 chain C against the predicted model Q92692: TM-score 0.95, RMSD 1.43 Å
- 5V52 chain D against the predicted model Q92692: TM-score 0.95, RMSD 1.46 Å
- 5V52 chain D against the predicted model Q92692: TM-score 0.95, RMSD 1.46 Å
- 4DFI chain A against the predicted model Q92692: TM-score 0.94, RMSD 1.59 Å
- 4DFI chain A against the predicted model Q92692: TM-score 0.94, RMSD 1.59 Å
Elsewhere
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