UniProt Q92608
Dedicator of cytokinesis protein 2 (Q92608)
Dedicator of cytokinesis protein 2 (UniProt Q92608): 11 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q92608
- Protein
- Dedicator of cytokinesis protein 2
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 15 · 1 record with a druggable one
Structures
12 records of Q92608 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2RQR | The solution structure of human DOCK2 SH3 domain - ELMO1 peptide chimera complex | solution nmr | A | — | — |
| 2RQR | The solution structure of human DOCK2 SH3 domain - ELMO1 peptide chimera complex | solution nmr | A | — | — |
| 2YIN | STRUCTURE OF THE COMPLEX BETWEEN Dock2 AND Rac1. | x-ray diffraction | A, B | — | — |
| 2YIN | Structure of the complex between DOCK2 and RAC1. | x-ray diffraction | A, B | — | — |
| 3A98 | Crystal structure of the complex of the interacting regions of DOCK2 and ELMO1 | x-ray diffraction | A, C | — | — |
| 3A98 | Crystal structure of the complex of the interacting regions of DOCK2 and ELMO1 | x-ray diffraction | A, C | — | — |
| 3B13 | Crystal structure of the DHR-2 domain of DOCK2 in complex with Rac1 (T17N mutant) | x-ray diffraction | A, C | — | — |
| 3B13 | Crystal structure of the dhr-2 domain of DOCK2 in complex with RAC1 (T17N mutant) | x-ray diffraction | A, C | — | — |
| 6TGB | CryoEM structure of the binary DOCK2-ELMO1 complex | electron microscopy | A, D | — | 15 (best 0.86) |
| 6TGB | Cryoem structure of the binary DOCK2-ELMO1 complex | electron microscopy | A, D | — | — |
| 6TGC | Cryoem structure of the ternary DOCK2-ELMO1-RAC1 complex | electron microscopy | A, D | — | — |
| Q92608 | AlphaFold monomer V2.0 prediction for dedicator of cytokinesis protein 2 (Q92608) | predicted | A | — | — |
Experiment against prediction
- 2YIN chain B against the predicted model Q92608: TM-score 0.97, RMSD 1.41 Å
- 2YIN chain B against the predicted model Q92608: TM-score 0.97, RMSD 1.41 Å
- 2YIN chain A against the predicted model Q92608: TM-score 0.96, RMSD 1.48 Å
- 2YIN chain A against the predicted model Q92608: TM-score 0.96, RMSD 1.48 Å
- 3B13 chain A against the predicted model Q92608: TM-score 0.96, RMSD 1.53 Å
- 3B13 chain A against the predicted model Q92608: TM-score 0.96, RMSD 1.53 Å
- 3B13 chain C against the predicted model Q92608: TM-score 0.96, RMSD 1.54 Å
- 3B13 chain C against the predicted model Q92608: TM-score 0.96, RMSD 1.54 Å
- 6TGB chain D against the predicted model Q92608: TM-score 0.93, RMSD 2.07 Å
- 6TGB chain D against the predicted model Q92608: TM-score 0.93, RMSD 2.07 Å
Elsewhere
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