UniProt Q92556
Engulfment and cell motility protein 1 (Q92556)
Engulfment and cell motility protein 1 (UniProt Q92556): 15 experimental structures and 1 predicted model on GenesisL1, 35 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q92556
- Protein
- Engulfment and cell motility protein 1
- Experimental structures
- 15
- Predicted models
- 1
- Pockets
- 35 · 5 records with a druggable one
Structures
16 records of Q92556 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2RQR | The solution structure of human DOCK2 SH3 domain - ELMO1 peptide chimera complex | solution nmr | A | — | — |
| 2RQR | The solution structure of human DOCK2 SH3 domain - ELMO1 peptide chimera complex | solution nmr | A | — | — |
| 2VSZ | Crystal Structure of the ELMO1 PH domain | x-ray diffraction | A, B | — | — |
| 2VSZ | Crystal structure of the ELMO1 pH domain | x-ray diffraction | A, B | — | — |
| 3A98 | Crystal structure of the complex of the interacting regions of DOCK2 and ELMO1 | x-ray diffraction | B, D | — | — |
| 3A98 | Crystal structure of the complex of the interacting regions of DOCK2 and ELMO1 | x-ray diffraction | B, D | — | — |
| 6JPP | Solution structure of ELMO1 rbd | solution nmr | A | — | — |
| 6TGB | CryoEM structure of the binary DOCK2-ELMO1 complex | electron microscopy | B | — | 9 (best 0.84) |
| 6TGB | Cryoem structure of the binary DOCK2-ELMO1 complex | electron microscopy | B | — | — |
| 6TGC | Cryoem structure of the ternary DOCK2-ELMO1-RAC1 complex | electron microscopy | B, E | — | — |
| 7DPA | Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex | electron microscopy | C, F | — | 5 (best 0.83) |
| 7DPA | Cryo-EM structure of the human ELMO1-DOCK5-RAC1 complex | electron microscopy | C, F | — | — |
| 7Y4A | Crystal structure of human ELMO1 RBD-RhoG complex | x-ray diffraction | B, D, F, H | — | 6 (best 0.79) |
| 8JHK | Cryo-EM structure of the DOCK5/ELMO1 complex, focused on one protomer | electron microscopy | A | — | 11 (best 0.80) |
| 8ZJK | Structure of DOCK5/ELMO1/Rac1 core (RhoG/DOCK5/ELMO1/Rac1 dataset, class 3) | electron microscopy | A, D | — | 4 (best 0.80) |
| Q92556 | AlphaFold monomer V2.0 prediction for engulfment and cell motility protein 1 (Q92556) | predicted | A | — | — |
Experiment against prediction
- 7Y4A chain F against the predicted model Q92556: TM-score 0.91, RMSD 0.71 Å
- 7Y4A chain B against the predicted model Q92556: TM-score 0.91, RMSD 0.70 Å
- 3A98 chain D against the predicted model Q92556: TM-score 0.90, RMSD 1.77 Å
- 3A98 chain D against the predicted model Q92556: TM-score 0.90, RMSD 1.77 Å
- 7Y4A chain D against the predicted model Q92556: TM-score 0.89, RMSD 0.90 Å
- 7Y4A chain H against the predicted model Q92556: TM-score 0.88, RMSD 0.99 Å
- 8ZJK chain D against the predicted model Q92556: TM-score 0.86, RMSD 2.46 Å
- 8ZJK chain A against the predicted model Q92556: TM-score 0.86, RMSD 2.46 Å
- 3A98 chain B against the predicted model Q92556: TM-score 0.84, RMSD 2.78 Å
- 3A98 chain B against the predicted model Q92556: TM-score 0.84, RMSD 2.78 Å
Elsewhere
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