UniProt Q92522
Histone H1x (Q92522)
Histone H1x (UniProt Q92522): 7 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q92522
- Protein
- Histone H1x
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
8 records of Q92522 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LSO | Solution NMR Structure of the Globular Domain of Human Histone H1x, Northeast Structural Genomics… | solution nmr | A | — | — |
| 2LSO | Solution NMR structure of the globular domain of human histone H1X, northeast structural genomics… | solution nmr | A | — | — |
| 6L9Z | 338 bp di-nucleosome assembled with linker histone H1.X | x-ray diffraction | S | — | — |
| 6L9Z | 338 bp di-nucleosome assembled with linker histone H1.X | x-ray diffraction | S | — | — |
| 7K60 | Cryo-EM structure of a chromatosome containing human linker histone H1.10 | electron microscopy | U | — | 1 (best 0.57) |
| 7K60 | Cryo-EM structure of a chromatosome containing human linker histone H1.10 | electron microscopy | U | — | — |
| 8YTI | Crystal Structure of Nucleosome-H1x Linker Histone Assembly (sticky-169a DNA fragment) | x-ray diffraction | U, V | — | — |
| Q92522 | AlphaFold monomer V2.0 prediction for histone H1.10 (Q92522) | predicted | A | — | 1 (best 0.31) |
Experiment against prediction
- 7K60 chain U against the predicted model Q92522: TM-score 0.95, RMSD 0.80 Å
- 7K60 chain U against the predicted model Q92522: TM-score 0.95, RMSD 0.80 Å
- 6L9Z chain S against the predicted model Q92522: TM-score 0.84, RMSD 2.04 Å
- 6L9Z chain S against the predicted model Q92522: TM-score 0.84, RMSD 2.04 Å
- 2LSO chain A against the predicted model Q92522: TM-score 0.81, RMSD 1.83 Å
- 2LSO chain A against the predicted model Q92522: TM-score 0.81, RMSD 1.83 Å
- 8YTI chain U against the predicted model Q92522: TM-score 0.79, RMSD 1.91 Å
- 8YTI chain V against the predicted model Q92522: TM-score 0.77, RMSD 2.38 Å
Elsewhere
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