UniProt Q921D4
Mediator of RNA polymerase II transcription subunit 6 (Q921D4)
Mediator of RNA polymerase II transcription subunit 6 (UniProt Q921D4): 4 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q921D4
- Protein
- Mediator of RNA polymerase II transcription subunit 6
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 4 · 2 records with a druggable one
Structures
5 records of Q921D4 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6W1S | Atomic model of the mammalian Mediator complex | electron microscopy | C | — | 2 (best 0.81) |
| 6W1S | Atomic model of the mammalian mediator complex | electron microscopy | C | — | — |
| 8T1I | Atomic model of the mammalian Mediator complex with MED26 subunit | electron microscopy | C | — | — |
| 8T1L | Atomic model of the mammalian mouse Mediator complex with CKM module | electron microscopy | C | — | 1 (best 0.84) |
| Q921D4 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 6 (Q921D4) | predicted | A | — | 1 (best 0.38) |
Experiment against prediction
- 6W1S chain C against the predicted model Q921D4: TM-score 0.71, RMSD 2.58 Å
- 6W1S chain C against the predicted model Q921D4: TM-score 0.71, RMSD 2.58 Å
- 8T1L chain C against the predicted model Q921D4: TM-score 0.56, RMSD 3.36 Å
- 8T1I chain C against the predicted model Q921D4: TM-score 0.40, RMSD 4.95 Å
Elsewhere
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