UniProt Q91XA9
Acidic mammalian chitinase (Q91XA9)
Acidic mammalian chitinase (UniProt Q91XA9), EC 3.2.1.14: 9 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 39 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q91XA9
- Protein
- Acidic mammalian chitinase
- EC
- 3.2.1.14
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 39 · 8 records with a druggable one
Structures
10 records of Q91XA9 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FG5 | Apo mouse acidic mammalian chitinase, catalytic domain at 100 K | x-ray diffraction | A | MG | — |
| 8FG7 | Apo mouse acidic mammalian chitinase, catalytic domain at 277 K | x-ray diffraction | A | MG | 1 (best 0.62) |
| 8FR9 | Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH… | x-ray diffraction | A, B | NAG, NDG, MG | 4 (best 0.78) |
| 8FRA | Mouse acidic mammalian chitinase, catalytic domain in complex with diacetylchitobiose at pH 5.60 | x-ray diffraction | A, B, C, D | NAG, NDG, MG | 7 (best 0.82) |
| 8FRB | Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH… | x-ray diffraction | A, B, C, D | NAG, HSQ, NDG, MG | 12 (best 0.80) |
| 8FRC | Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH… | x-ray diffraction | A, B | NAG | 3 (best 0.76) |
| 8FRD | Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH… | x-ray diffraction | A, B | NAG, MG | 3 (best 0.77) |
| 8FRG | Mouse acidic mammalian chitinase, catalytic domain in complex with N,N'-diacetylchitobiose at pH… | x-ray diffraction | A, B | NAG, NDG, MG | 4 (best 0.65) |
| 8GCA | Mouse acidic mammalian chitinase, catalytic domain in complex with N,N',N''-triacetylchitotriose at… | x-ray diffraction | A, B | NAG, MG | 5 (best 0.66) |
| Q91XA9 | AlphaFold monomer V2.0 prediction for acidic mammalian chitinase (Q91XA9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8FRG chain B against the predicted model Q91XA9: TM-score 1.00, RMSD 0.38 Å
- 8FRC chain B against the predicted model Q91XA9: TM-score 1.00, RMSD 0.40 Å
- 8FRD chain B against the predicted model Q91XA9: TM-score 1.00, RMSD 0.41 Å
- 8FRB chain D against the predicted model Q91XA9: TM-score 1.00, RMSD 0.42 Å
- 8FRB chain A against the predicted model Q91XA9: TM-score 1.00, RMSD 0.43 Å
- 8FRA chain B against the predicted model Q91XA9: TM-score 1.00, RMSD 0.43 Å
- 8FRG chain A against the predicted model Q91XA9: TM-score 1.00, RMSD 0.46 Å
- 8FRD chain A against the predicted model Q91XA9: TM-score 1.00, RMSD 0.47 Å
- 8FRC chain A against the predicted model Q91XA9: TM-score 1.00, RMSD 0.47 Å
- 8FRA chain A against the predicted model Q91XA9: TM-score 1.00, RMSD 0.49 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.