UniProt Q90VU7
Protein Nef (Q90VU7)
Protein Nef (UniProt Q90VU7): 15 experimental structures on GenesisL1, 7 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q90VU7
- Protein
- Protein Nef
- Experimental structures
- 15
- Predicted models
- 0
- Pockets
- 7 · 1 record with a druggable one
Structures
15 records of Q90VU7 in the MolNFT archive: 15 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4EMZ | HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second… | x-ray diffraction | C, B | — | — |
| 4EMZ | HIV-1 nef in complex with MHC-I cytoplasmic domain and MU1 adaptin subunit of AP1 adaptor (second… | x-ray diffraction | C, B | — | — |
| 4EN2 | HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second… | x-ray diffraction | B, C | — | — |
| 4EN2 | HIV-1 nef in complex with MHC-I cytoplasmic domain and MU1 adaptin subunit of AP1 adaptor (second… | x-ray diffraction | B, C | — | — |
| 4NEE | crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef | x-ray diffraction | E, H, K, C | — | — |
| 4NEE | Crystal structure of ap-2 ALPHA/SIMGA2 complex bound to HIV-1 nef | x-ray diffraction | E, H, K, C | — | — |
| 6CM9 | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef closed trimer monomeric subunit | electron microscopy | L, T, N | — | — |
| 6CRI | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef stable closed trimer | electron microscopy | T, N, c, Y, d, Z | — | — |
| 6D83 | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef (L164A, L165A) dileucine mutant dimer monomeric… | electron microscopy | T, L | — | — |
| 6D84 | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef (L164A, L165A) dileucine mutant dimer | electron microscopy | T, L, R, O | — | — |
| 6DFF | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef monomer | electron microscopy | L, T | — | — |
| 6URI | HIV-1 nef in complex with the CD4 cytoplasmic domain and the AP2 clathrin adaptor complex | x-ray diffraction | N | — | — |
| 8D9R | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on… | electron microscopy | N, L, o, e, p, f, q, g, r, h, s, i | — | 7 (best 0.74) |
| 8D9T | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on… | electron microscopy | N, L, n, d, o, e, p, f, q, g, r, h | — | — |
| 8D9U | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on… | electron microscopy | N, L, n, d, o, e, p, f, q, g, r, h | — | — |
Experiment against prediction
- 6D84 chain O against the predicted model Q10589: TM-score 0.41, RMSD 1.07 Å
- 6D84 chain L against the predicted model Q10589: TM-score 0.41, RMSD 1.07 Å
- 6D83 chain L against the predicted model Q10589: TM-score 0.40, RMSD 1.12 Å
- 6CM9 chain L against the predicted model Q10589: TM-score 0.36, RMSD 1.80 Å
- 6CRI chain T against the predicted model Q10589: TM-score 0.35, RMSD 1.73 Å
- 6CRI chain c against the predicted model Q10589: TM-score 0.35, RMSD 1.73 Å
- 6CRI chain d against the predicted model Q10589: TM-score 0.35, RMSD 1.73 Å
- 6DFF chain L against the predicted model Q10589: TM-score 0.34, RMSD 0.91 Å
- 6DFF chain T against the predicted model Q10589: TM-score 0.32, RMSD 1.82 Å
- 6D84 chain T against the predicted model Q10589: TM-score 0.32, RMSD 1.68 Å
Elsewhere
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