UniProt Q8ZIE7
D-alanine--D-alanine ligase (Q8ZIE7)
D-alanine--D-alanine ligase (UniProt Q8ZIE7), EC 6.3.2.4: 12 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 125 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8ZIE7
- Protein
- D-alanine--D-alanine ligase
- EC
- 6.3.2.4
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 125 · 13 records with a druggable one
Structures
13 records of Q8ZIE7 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3V4Z | D-alanine--D-alanine ligase from Yersinia pestis | x-ray diffraction | A, B | — | 5 (best 0.67) |
| 3V4Z | D-alanine--D-alanine ligase from yersinia pestis | x-ray diffraction | A, B | — | 5 (best 0.67) |
| 4ZQI | Crystal structure of Apo D-alanine-D-alanine ligase(DDL) from Yersinia pestis | x-ray diffraction | A, B, C, D | NA | 13 (best 0.77) |
| 4ZQI | Crystal structure of apo D-alanine-D-alanine LIGASE(DDL) from yersinia pestis | x-ray diffraction | A, B, C, D | NA | 13 (best 0.77) |
| 5BPF | Crystal structure of ADP complexed D-alanine-D-alanine ligase(DDL) from Yersinia pestis | x-ray diffraction | A, B, C, D | NA, ADP | 10 (best 0.80) |
| 5BPF | Crystal structure of ADP complexed D-alanine-D-alanine LIGASE(DDL) from yersinia pestis | x-ray diffraction | A, B, C, D | NA, ADP | 10 (best 0.80) |
| 5BPH | Crystal structure of AMP complexed D-alanine-D-alanine ligase(DDL) from Yersinia pestis | x-ray diffraction | A, B, C, D | AMP, NA | 11 (best 0.88) |
| 5BPH | Crystal structure of AMP complexed D-alanine-D-alanine LIGASE(DDL) from yersinia pestis | x-ray diffraction | A, B, C, D | AMP, NA | 11 (best 0.88) |
| 5C1O | Crystal structure of AMP-PNP complexed D-alanine-D-alanine ligase(DDL) from Yersinia pestis | x-ray diffraction | A, B, C, D | ANP, NA, MG | 11 (best 0.80) |
| 5C1O | Crystal structure of AMP-pnp complexed D-alanine-D-alanine LIGASE(DDL) from yersinia pestis | x-ray diffraction | A, B, C, D | ANP, NA, MG | 11 (best 0.80) |
| 5C1P | Crystal structure of ADP and D-alanyl-D-alanine complexed D-alanine-D-alanine ligase(DDL) from… | x-ray diffraction | A, B, C, D | NA, ADP | 12 (best 0.79) |
| 5C1P | Crystal structure of ADP and D-alanyl-D-alanine complexed D-alanine-D- alanine LIGASE(DDL) from… | x-ray diffraction | A, B, C, D | NA, ADP | 12 (best 0.79) |
| Q8ZIE7 | AlphaFold monomer V2.0 prediction for D-alanine--D-alanine ligase (Q8ZIE7) | predicted | A | — | 1 (best 0.81) |
Ligands
Experiment against prediction
- 3V4Z chain A against the predicted model Q8ZIE7: TM-score 0.99, RMSD 0.84 Å
- 3V4Z chain A against the predicted model Q8ZIE7: TM-score 0.99, RMSD 0.84 Å
- 5C1O chain D against the predicted model Q8ZIE7: TM-score 0.97, RMSD 1.05 Å
- 5C1O chain D against the predicted model Q8ZIE7: TM-score 0.97, RMSD 1.05 Å
- 5C1O chain B against the predicted model Q8ZIE7: TM-score 0.97, RMSD 1.06 Å
- 5C1O chain B against the predicted model Q8ZIE7: TM-score 0.97, RMSD 1.06 Å
- 5C1P chain C against the predicted model Q8ZIE7: TM-score 0.97, RMSD 1.13 Å
- 5C1P chain C against the predicted model Q8ZIE7: TM-score 0.97, RMSD 1.13 Å
- 5BPF chain C against the predicted model Q8ZIE7: TM-score 0.97, RMSD 1.13 Å
- 5BPF chain C against the predicted model Q8ZIE7: TM-score 0.97, RMSD 1.13 Å
Elsewhere
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