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UniProt Q8YIN7

7-alpha-hydroxysteroid dehydrogenase (Q8YIN7)

7-alpha-hydroxysteroid dehydrogenase (UniProt Q8YIN7), EC 1.1.1.159: 10 experimental structures on GenesisL1, 1 ligand bound, 129 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8YIN7
Protein
7-alpha-hydroxysteroid dehydrogenase
EC
1.1.1.159
Experimental structures
10
Predicted models
0
Ligands
1
Pockets
129 · 10 records with a druggable one

Structures

10 records of Q8YIN7 in the MolNFT archive: 10 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
3GAF2.2A Crystal Structure of 7-Alpha-Hydroxysteroid Dehydrogenase from Brucella Melitensisx-ray diffractionA, B, C, D, E, F, G, H—19 (best 0.81)
3GAF2.2A crystal structure of 7-alpha-hydroxysteroid dehydrogenase from brucella melitensisx-ray diffractionA, B, C, D, E, F, G, H—19 (best 0.81)
8HAXBrucella melitensis 7alpha-Hydroxysteroid Dehydrogenase mutant-I258M/K262Tx-ray diffractionA, B, C, D—10 (best 0.82)
8HDIBrucella melitensis 7-alpha-Hydroxysteroid Dehydrogenase mutant: 1-53 truncation/K262Tx-ray diffractionA, B, C, D—10 (best 0.82)
8HDNBrucella melitensis 7-alpha-Hydroxysteroid Dehydrogenase mutant: 1-53 truncation-I258M/K262Tx-ray diffractionA, B, C, D—10 (best 0.81)
8HS4Brucella melitensis 7-alpha-Hydroxysteroid Dehydrogenase mutant: 1-53 truncation/K262T-NAD+x-ray diffractionA, BNAD6 (best 0.55)
8HS5Brucella melitensis 7-alpha-Hydroxysteroid Dehydrogenase mutant: 1-53 truncation-I258M/K262T-NAD+x-ray diffractionA, BNAD6 (best 0.56)
8HS6Brucella melitensis 7-alpha-Hydroxysteroid Dehydrogenase mutant:1-53 truncationx-ray diffractionA, B, C, D, E, F, G, H, I, J, K, L—20 (best 0.82)
8HS9Brucella melitensis 7-alpha-Hydroxysteroid Dehydrogenase mutant:I258M/K262Tx-ray diffractionE, A, B, C—9 (best 0.82)
8HSABrucella melitensis 7-alpha-Hydroxysteroid Dehydrogenase mutant: 1-53…x-ray diffractionG, A, B, C, D, E, F, HNAD20 (best 0.82)

Ligands

  • NAD · Nicotinamide-adenine-dinucleotide · in 3 records

Elsewhere

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