UniProt Q8YC53
Blue-light-activated histidine kinase (Q8YC53)
Blue-light-activated histidine kinase (UniProt Q8YC53), EC 2.7.13.3: 8 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 34 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8YC53
- Protein
- Blue-light-activated histidine kinase
- EC
- 2.7.13.3
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 34 · 4 records with a druggable one
Structures
9 records of Q8YC53 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3T50 | X-ray structure of the LOV domain from the LOV-HK sensory protein from Brucella abortus (dark… | x-ray diffraction | A, B | — | — |
| 3T50 | X-ray structure of the lov domain from the lov-hk sensory protein from brucella abortus (dark… | x-ray diffraction | A, B | — | — |
| 6PH2 | Complete LOV domain from the LOV-HK sensory protein from Brucella abortus (mutant C69S, construct… | x-ray diffraction | A, B, C, D | FMN | 8 (best 0.68) |
| 6PH2 | Complete lov domain from the lov-hk sensory protein from brucella abortus (mutant C69S, construct… | x-ray diffraction | A, B, C, D | FMN | — |
| 6PH3 | LOV-PAS construct from the LOV-HK sensory protein from Brucella abortus (dark-adapted, construct… | x-ray diffraction | A, B, C, D | FMN | 10 (best 0.78) |
| 6PH3 | Lov-pas construct from the lov-hk sensory protein from brucella abortus (dark-adapted, construct… | x-ray diffraction | A, B, C, D | FMN | — |
| 6PH4 | Full length LOV-PAS-HK construct from the LOV-HK sensory protein from Brucella abortus… | x-ray diffraction | A, B | CL, FMN, MG, ACP | 12 (best 0.77) |
| 6PH4 | Full length lov-pas-hk construct from the lov-hk sensory protein from brucella abortus… | x-ray diffraction | A, B | CL, FMN, MG, ACP | — |
| Q8YC53 | AlphaFold monomer V2.0 prediction for blue-light-activated histidine kinase (Q8YC53) | predicted | A | — | 4 (best 0.73) |
Ligands
Experiment against prediction
- 6PH2 chain B against the predicted model Q8YC53: TM-score 0.99, RMSD 0.34 Å
- 6PH2 chain B against the predicted model Q8YC53: TM-score 0.99, RMSD 0.34 Å
- 6PH2 chain D against the predicted model Q8YC53: TM-score 0.99, RMSD 0.40 Å
- 6PH2 chain D against the predicted model Q8YC53: TM-score 0.99, RMSD 0.40 Å
- 6PH2 chain A against the predicted model Q8YC53: TM-score 0.99, RMSD 0.47 Å
- 6PH2 chain A against the predicted model Q8YC53: TM-score 0.99, RMSD 0.47 Å
- 6PH2 chain C against the predicted model Q8YC53: TM-score 0.99, RMSD 0.48 Å
- 6PH2 chain C against the predicted model Q8YC53: TM-score 0.99, RMSD 0.48 Å
- 3T50 chain B against the predicted model Q8YC53: TM-score 0.98, RMSD 0.65 Å
- 3T50 chain B against the predicted model Q8YC53: TM-score 0.98, RMSD 0.65 Å
Elsewhere
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