UniProt Q8WZM4
2,4-dienoyl-CoA reductase (Q8WZM4)
2,4-dienoyl-CoA reductase (UniProt Q8WZM4), EC 1.3.1.10, 1.3.1.38: 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8WZM4
- Protein
- 2,4-dienoyl-CoA reductase
- EC
- 1.3.1.10, 1.3.1.38
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 1 record with a druggable one
Structures
5 records of Q8WZM4 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H0K | Enoyl thioester reductase 2 | x-ray diffraction | A, B | SO4 | 7 (best 0.76) |
| 1H0K | Enoyl thioester reductase 2 | x-ray diffraction | A, B | — | — |
| 1N9G | Mitochondrial 2-enoyl thioester reductase Etr1p/Etr2p heterodimer from Candida tropicalis | x-ray diffraction | A, C, F | — | — |
| 1N9G | Mitochondrial 2-enoyl thioester reductase ETR1P/ETR2P heterodimer from candida tropicalis | x-ray diffraction | A, C, F | — | — |
| Q8WZM4 | AlphaFold monomer V2.0 prediction for enoyl-[acyl-carrier-protein] reductase 2, mitochondrial… | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 1H0K chain A against the predicted model Q8WZM4: TM-score 1.00, RMSD 0.46 Å
- 1H0K chain A against the predicted model Q8WZM4: TM-score 1.00, RMSD 0.46 Å
- 1N9G chain A against the predicted model Q8WZM4: TM-score 0.99, RMSD 0.50 Å
- 1N9G chain A against the predicted model Q8WZM4: TM-score 0.99, RMSD 0.50 Å
- 1N9G chain F against the predicted model Q8WZM4: TM-score 0.99, RMSD 0.51 Å
- 1N9G chain F against the predicted model Q8WZM4: TM-score 0.99, RMSD 0.51 Å
- 1H0K chain B against the predicted model Q8WZM4: TM-score 0.99, RMSD 0.56 Å
- 1H0K chain B against the predicted model Q8WZM4: TM-score 0.99, RMSD 0.56 Å
- 1N9G chain C against the predicted model Q8WZM4: TM-score 0.98, RMSD 1.10 Å
- 1N9G chain C against the predicted model Q8WZM4: TM-score 0.98, RMSD 1.10 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.