UniProt Q8WVS4

Cytoplasmic dynein 2 intermediate chain 1 (Q8WVS4)

Cytoplasmic dynein 2 intermediate chain 1 (UniProt Q8WVS4): 6 experimental structures and 1 predicted model on GenesisL1, 34 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q8WVS4
Protein: Cytoplasmic dynein 2 intermediate chain 1
Experimental structures: 6
Predicted models: 1
Pockets: 34 · 4 records with a druggable one

Structures

7 records of Q8WVS4 in the MolNFT archive: 6 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6RLB	Structure of the dynein-2 complex; tail domain	electron microscopy	C	—	9 (best 0.80)
6RLB	Structure of the dynein-2 complex; tail domain	electron microscopy	C	—	—
6SC2	Structure of the dynein-2 complex; IFT-train bound model	electron microscopy	C	—	6 (best 0.81)
6SC2	Structure of the dynein-2 complex; ift-train bound model	electron microscopy	C	—	—
8RGG	Structure of dynein-2 intermediate chain DYNC2I2 (WDR34) in complex with dynein-2 heavy chain…	electron microscopy	C	—	4 (best 0.80)
8RGH	Structure of dynein-2 intermediate chain DYNC2I1 (WDR60) in complex with the dynein-2 heavy chain…	electron microscopy	C	—	15 (best 0.84)
Q8WVS4	AlphaFold monomer V2.0 prediction for cytoplasmic dynein 2 intermediate chain 1 (Q8WVS4)	predicted	A	—	—

Experiment against prediction

8RGH chain C against the predicted model Q8WVS4: TM-score 0.92, RMSD 2.58 Å
6SC2 chain C against the predicted model Q8WVS4: TM-score 0.85, RMSD 3.43 Å
6SC2 chain C against the predicted model Q8WVS4: TM-score 0.85, RMSD 3.43 Å
6RLB chain C against the predicted model Q8WVS4: TM-score 0.85, RMSD 3.43 Å
6RLB chain C against the predicted model Q8WVS4: TM-score 0.85, RMSD 3.43 Å
8RGG chain C against the predicted model Q8WVS4: TM-score 0.71, RMSD 1.91 Å

Elsewhere

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