UniProt Q8WVM0
Dimethyladenosine transferase 1, mitochondrial (Q8WVM0)
Dimethyladenosine transferase 1, mitochondrial (UniProt Q8WVM0), EC 2.1.1.-: 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 25 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8WVM0
- Protein
- Dimethyladenosine transferase 1, mitochondrial
- EC
- 2.1.1.-
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 25 · 6 records with a druggable one
Structures
8 records of Q8WVM0 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6AAX | Crystal structure of TFB1M and h45 with SAM in homo sapiens | x-ray diffraction | A, C | SAM | 7 (best 0.74) |
| 6AAX | Crystal structure of TFB1M and H45 with SAM in homo sapiens | x-ray diffraction | A, C | — | — |
| 6AJK | Crystal structure of TFB1M and H45 in homo sapiens | x-ray diffraction | A | — | — |
| 8CSP | Human mitochondrial small subunit assembly intermediate (State A) | electron microscopy | 5 | — | 3 (best 0.76) |
| 8CSQ | Human mitochondrial small subunit assembly intermediate (State B) | electron microscopy | 5 | — | 4 (best 0.80) |
| 8CSR | Human mitochondrial small subunit assembly intermediate (State C) | electron microscopy | 5 | — | 5 (best 0.83) |
| 8CSU | Human mitochondrial small subunit assembly intermediate (State C*) | electron microscopy | 5 | — | 3 (best 0.85) |
| Q8WVM0 | AlphaFold monomer V2.0 prediction for dimethyladenosine transferase 1, mitochondrial (Q8WVM0) | predicted | A | — | 3 (best 0.71) |
Ligands
- SAM · S-adenosylmethionine · in 1 record
Experiment against prediction
- 6AAX chain A against the predicted model Q8WVM0: TM-score 0.99, RMSD 0.67 Å
- 6AJK chain A against the predicted model Q8WVM0: TM-score 0.99, RMSD 0.70 Å
- 6AAX chain C against the predicted model Q8WVM0: TM-score 0.99, RMSD 0.71 Å
- 6AAX chain A against the predicted model Q8WVM0: TM-score 0.99, RMSD 0.67 Å
- 6AAX chain C against the predicted model Q8WVM0: TM-score 0.98, RMSD 0.71 Å
- 8CSP chain 5 against the predicted model Q8WVM0: TM-score 0.96, RMSD 1.66 Å
- 8CSQ chain 5 against the predicted model Q8WVM0: TM-score 0.96, RMSD 1.68 Å
- 8CSR chain 5 against the predicted model Q8WVM0: TM-score 0.96, RMSD 1.72 Å
- 8CSU chain 5 against the predicted model Q8WVM0: TM-score 0.96, RMSD 1.73 Å
Elsewhere
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