UniProt Q8WVB6
Chromosome transmission fidelity protein 18 homolog (Q8WVB6)
Chromosome transmission fidelity protein 18 homolog (UniProt Q8WVB6): 7 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 59 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8WVB6
- Protein
- Chromosome transmission fidelity protein 18 homolog
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 59 · 7 records with a druggable one
Structures
8 records of Q8WVB6 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8UMT | Atomic model of the human CTF18-RFC-PCNA binary complex in the three-subunit binding state (state 2) | electron microscopy | A | ADP | 9 (best 0.88) |
| 8UMU | Atomic model of the human CTF18-RFC-PCNA binary complex in the four-subunit binding state (state 3) | electron microscopy | A | MG, AGS, ADP | 10 (best 0.85) |
| 8UMV | Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening state I… | electron microscopy | A | MG, AGS, ADP | 7 (best 0.88) |
| 8UMW | Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex in the five-subunit binding state… | electron microscopy | A | MG, AGS, ADP | 9 (best 0.87) |
| 8UMY | Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening state II… | electron microscopy | A | MG, AGS, ADP | 11 (best 0.87) |
| 8UN0 | Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with cracked and closed PCNA (state 7) | electron microscopy | A | MG, AGS, ADP | 8 (best 0.86) |
| 8UNJ | Atomic model of the human CTF18-RFC alone in the apo state (State 1) | electron microscopy | A | ADP | 5 (best 0.87) |
| Q8WVB6 | AlphaFold monomer V2.0 prediction for chromosome transmission fidelity protein 18 homolog (Q8WVB6) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8UMY chain A against the predicted model Q8WVB6: TM-score 0.86, RMSD 3.04 Å
- 8UMV chain A against the predicted model Q8WVB6: TM-score 0.86, RMSD 3.14 Å
- 8UMW chain A against the predicted model Q8WVB6: TM-score 0.86, RMSD 3.18 Å
- 8UN0 chain A against the predicted model Q8WVB6: TM-score 0.85, RMSD 3.23 Å
- 8UNJ chain A against the predicted model Q8WVB6: TM-score 0.79, RMSD 1.70 Å
- 8UMU chain A against the predicted model Q8WVB6: TM-score 0.56, RMSD 5.29 Å
- 8UMT chain A against the predicted model Q8WVB6: TM-score 0.53, RMSD 4.74 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.