UniProt Q8WUW1
Protein BRICK1 (Q8WUW1)
Protein BRICK1 (UniProt Q8WUW1): 7 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8WUW1
- Protein
- Protein BRICK1
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 15 · 3 records with a druggable one
Structures
8 records of Q8WUW1 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3P8C | Structure and Control of the Actin Regulatory WAVE Complex | x-ray diffraction | E | — | — |
| 3P8C | Structure and control of the actin regulatory wave complex | x-ray diffraction | E | — | — |
| 4N78 | The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton | x-ray diffraction | E | — | — |
| 4N78 | The wave regulatory complex links diverse receptors to the actin cytoskeleton | x-ray diffraction | E | — | — |
| 7USC | Cryo-EM structure of WAVE Regulatory Complex | electron microscopy | D | — | 5 (best 0.83) |
| 7USD | Cryo-EM structure of D-site Rac1-bound WAVE Regulatory Complex | electron microscopy | D | — | 6 (best 0.81) |
| 7USE | Cryo-EM structure of WAVE regulatory complex with Rac1 bound on both A and D site | electron microscopy | D | — | 4 (best 0.80) |
| Q8WUW1 | AlphaFold monomer V2.0 prediction for protein BRICK1 (Q8WUW1) | predicted | A | — | — |
Experiment against prediction
- 7USD chain D against the predicted model Q8WUW1: TM-score 0.95, RMSD 0.67 Å
- 7USE chain D against the predicted model Q8WUW1: TM-score 0.94, RMSD 1.26 Å
- 3P8C chain E against the predicted model Q8WUW1: TM-score 0.91, RMSD 0.73 Å
- 3P8C chain E against the predicted model Q8WUW1: TM-score 0.91, RMSD 0.73 Å
- 7USC chain D against the predicted model Q8WUW1: TM-score 0.91, RMSD 0.87 Å
- 4N78 chain E against the predicted model Q8WUW1: TM-score 0.90, RMSD 0.87 Å
- 4N78 chain E against the predicted model Q8WUW1: TM-score 0.90, RMSD 0.87 Å
Elsewhere
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