UniProt Q8WUA2

Peptidyl-prolyl cis-trans isomerase-like 4 (Q8WUA2)

Peptidyl-prolyl cis-trans isomerase-like 4 (UniProt Q8WUA2), EC 5.2.1.8: 6 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q8WUA2
Protein: Peptidyl-prolyl cis-trans isomerase-like 4
EC: 5.2.1.8
Experimental structures: 6
Predicted models: 1
Pockets: 3 · 2 records with a druggable one

Structures

7 records of Q8WUA2 in the MolNFT archive: 6 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7QTT	Structural organization of a late activated human spliceosome (Baqr, core region)	electron microscopy	V	—	—
8CH6	Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius…	electron microscopy	V	—	—
8I0S	The cryo-EM structure of human Bact-II complex	electron microscopy	Y	—	—
8I0T	The cryo-EM structure of human Bact-III complex	electron microscopy	Y	—	—
8I0U	The cryo-EM structure of human Bact-IV complex	electron microscopy	Y	—	1 (best 0.82)
8I0V	The cryo-EM structure of human post-Bact complex	electron microscopy	Y	—	1 (best 0.81)
Q8WUA2	AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase-like 4 (Q8WUA2)	predicted	A	—	1 (best 0.31)

Experiment against prediction

8I0S chain Y against the predicted model Q8WUA2: TM-score 0.63, RMSD 1.60 Å
8I0T chain Y against the predicted model Q8WUA2: TM-score 0.63, RMSD 1.60 Å
8I0U chain Y against the predicted model Q8WUA2: TM-score 0.63, RMSD 1.62 Å
8I0V chain Y against the predicted model Q8WUA2: TM-score 0.63, RMSD 1.62 Å
7QTT chain V against the predicted model Q8WUA2: TM-score 0.59, RMSD 1.92 Å
8CH6 chain V against the predicted model Q8WUA2: TM-score 0.59, RMSD 1.93 Å

Elsewhere

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