UniProt Q8WNV7
Dehydrogenase/reductase SDR family member 4 (Q8WNV7)
Dehydrogenase/reductase SDR family member 4 (UniProt Q8WNV7), EC 1.1.1.184: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8WNV7
- Protein
- Dehydrogenase/reductase SDR family member 4
- EC
- 1.1.1.184
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 1 record with a druggable one
Structures
3 records of Q8WNV7 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2ZAT | Crystal structure of a mammalian reductase | x-ray diffraction | A, B, C, D | NAP | 12 (best 0.79) |
| 2ZAT | Crystal structure of a mammalian reductase | x-ray diffraction | A, B, C, D | — | — |
| Q8WNV7 | AlphaFold monomer V2.0 prediction for DEHYDROGENASE/REDUCTASE sdr family member 4 (Q8WNV7) | predicted | A | — | — |
Ligands
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · in 1 record
Experiment against prediction
- 2ZAT chain A against the predicted model Q8WNV7: TM-score 0.99, RMSD 0.87 Å
- 2ZAT chain A against the predicted model Q8WNV7: TM-score 0.99, RMSD 0.87 Å
- 2ZAT chain C against the predicted model Q8WNV7: TM-score 0.99, RMSD 0.89 Å
- 2ZAT chain C against the predicted model Q8WNV7: TM-score 0.99, RMSD 0.89 Å
- 2ZAT chain D against the predicted model Q8WNV7: TM-score 0.98, RMSD 0.90 Å
- 2ZAT chain D against the predicted model Q8WNV7: TM-score 0.98, RMSD 0.90 Å
- 2ZAT chain B against the predicted model Q8WNV7: TM-score 0.98, RMSD 0.92 Å
- 2ZAT chain B against the predicted model Q8WNV7: TM-score 0.98, RMSD 0.92 Å
Elsewhere
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