UniProt Q8VZG8
MDIS1-interacting receptor like kinase 2 (Q8VZG8)
MDIS1-interacting receptor like kinase 2 (UniProt Q8VZG8), EC 2.7.11.1: 5 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 29 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8VZG8
- Protein
- MDIS1-interacting receptor like kinase 2
- EC
- 2.7.11.1
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 29 · 4 records with a druggable one
Structures
6 records of Q8VZG8 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8WEB | Crystal structure of Arabidopsis thaliana MIK2 ectodomain | x-ray diffraction | A | NAG | — |
| 8WEC | Crystal structure of Arabidopsis thaliana MIK2 ectodomain in complex with BAK1 ectodomain and… | x-ray diffraction | A, D | NAG, FUC, BMA | 9 (best 0.69) |
| 8WED | Crystal structure of Arabidopsis thaliana MIK2 ectodomain in complex with BAK1 ectodomain and… | x-ray diffraction | A, D | NAG, BMA, FUC | 12 (best 0.69) |
| 8WEE | Crystal structure of Arabidopsis thaliana MIK2 ectodomain in complex with SCOOP12 | x-ray diffraction | A | NAG, FUC | — |
| 8YAA | Cryo-EM structure of MIK2-SCOOP12-BAK1 | electron microscopy | A | NAG | 4 (best 0.58) |
| Q8VZG8 | AlphaFold monomer V2.0 prediction for MDIS1-interacting receptor like kinase 2 (Q8VZG8) | predicted | A | — | 4 (best 0.81) |
Ligands
Experiment against prediction
- 8WED chain A against the predicted model Q8VZG8: TM-score 0.99, RMSD 0.98 Å
- 8WEC chain A against the predicted model Q8VZG8: TM-score 0.99, RMSD 1.00 Å
- 8WEE chain A against the predicted model Q8VZG8: TM-score 0.99, RMSD 1.02 Å
- 8WEB chain A against the predicted model Q8VZG8: TM-score 0.99, RMSD 1.01 Å
- 8YAA chain A against the predicted model Q8VZG8: TM-score 0.98, RMSD 1.29 Å
Elsewhere
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