UniProt Q8VYZ0
E3 ubiquitin-protein ligase ORTHRUS 2 (Q8VYZ0)
E3 ubiquitin-protein ligase ORTHRUS 2 (UniProt Q8VYZ0), EC 2.3.2.27: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 3 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8VYZ0
- Protein
- E3 ubiquitin-protein ligase ORTHRUS 2
- EC
- 2.3.2.27
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
3 records of Q8VYZ0 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7DUF | Crystal structure of VIM1 PHD finger. | x-ray diffraction | A, B | ZN | 1 (best 0.37) |
| 7DUF | Crystal structure of VIM1 phd finger. | x-ray diffraction | A, B | ZN | — |
| Q8VYZ0 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase orthrus 2 (Q8VYZ0) | predicted | A | — | 2 (best 0.54) |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 7DUF chain B against the predicted model Q8VYZ0: TM-score 0.89, RMSD 1.04 Å
- 7DUF chain B against the predicted model Q8VYZ0: TM-score 0.89, RMSD 1.04 Å
- 7DUF chain A against the predicted model Q8VYZ0: TM-score 0.87, RMSD 1.27 Å
- 7DUF chain A against the predicted model Q8VYZ0: TM-score 0.87, RMSD 1.27 Å
Elsewhere
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