UniProt Q8VE49
Dual oxidase maturation factor 1 (Q8VE49)
Dual oxidase maturation factor 1 (UniProt Q8VE49): 6 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8VE49
- Protein
- Dual oxidase maturation factor 1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 25 · 3 records with a druggable one
Structures
7 records of Q8VE49 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WXR | CryoEM structure of mouse DUOX1-DUOXA1 complex in the absence of NADPH | electron microscopy | B | NAG, MAN | 7 (best 0.85) |
| 6WXR | Cryoem structure of mouse DUOX1-DUOXA1 complex in the absence of NADPH | electron microscopy | B | NAG, MAN | — |
| 6WXU | CryoEM structure of mouse DUOX1-DUOXA1 complex in the dimer-of-dimer state | electron microscopy | B, D | NAG, BMA, MAN, PLC | 14 (best 0.86) |
| 6WXU | Cryoem structure of mouse DUOX1-DUOXA1 complex in the dimer-of-dimer state | electron microscopy | B, D | NAG, MAN, PLC | — |
| 6WXV | CryoEM structure of mouse DUOX1-DUOXA1 complex in the presence of NADPH | electron microscopy | B | NAG, MAN | 4 (best 0.84) |
| 6WXV | Cryoem structure of mouse DUOX1-DUOXA1 complex in the presence of NADPH | electron microscopy | B | NAG, MAN | — |
| Q8VE49 | AlphaFold monomer V2.0 prediction for dual oxidase maturation factor 1 (Q8VE49) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6WXU chain D against the predicted model Q8VE49: TM-score 0.97, RMSD 1.17 Å
- 6WXU chain D against the predicted model Q8VE49: TM-score 0.97, RMSD 1.17 Å
- 6WXU chain B against the predicted model Q8VE49: TM-score 0.97, RMSD 1.17 Å
- 6WXU chain B against the predicted model Q8VE49: TM-score 0.97, RMSD 1.17 Å
- 6WXR chain B against the predicted model Q8VE49: TM-score 0.97, RMSD 1.13 Å
- 6WXR chain B against the predicted model Q8VE49: TM-score 0.97, RMSD 1.13 Å
- 6WXV chain B against the predicted model Q8VE49: TM-score 0.96, RMSD 1.21 Å
- 6WXV chain B against the predicted model Q8VE49: TM-score 0.96, RMSD 1.21 Å
Elsewhere
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