UniProt Q8VDU0
G-protein-signaling modulator 2 (Q8VDU0)
G-protein-signaling modulator 2 (UniProt Q8VDU0): 18 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8VDU0
- Protein
- G-protein-signaling modulator 2
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 4 · 0 records with a druggable one
Structures
19 records of Q8VDU0 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3RO2 | Structures of the LGN/NuMA complex | x-ray diffraction | A | — | — |
| 3RO2 | Structures of the LGN/NUMA complex | x-ray diffraction | A | — | — |
| 3RO3 | crystal structure of LGN/mInscuteable complex | x-ray diffraction | A | — | — |
| 3RO3 | Crystal structure of LGN/MINSCUTEABLE complex | x-ray diffraction | A | — | — |
| 4G2V | Structure complex of LGN binding with FRMPD1 | x-ray diffraction | A | — | — |
| 4G2V | Structure complex of lgn binding with FRMPD1 | x-ray diffraction | A | — | — |
| 4G5O | Structure of LGN GL4/Galphai3(Q147L) complex | x-ray diffraction | E, F, G, H | — | — |
| 4G5O | Structure of lgn GL4/GALPHAI3(Q147L) complex | x-ray diffraction | E, F, G, H | — | — |
| 4G5Q | Structure of LGN GL4/Galphai1 complex | x-ray diffraction | E, F, G, H | — | — |
| 4G5Q | Structure of lgn GL4/GALPHAI1 complex | x-ray diffraction | E, F, G, H | — | — |
| 4G5R | Structure of LGN GL4/Galphai3 complex | x-ray diffraction | E, F, G, Z | — | — |
| 4G5R | Structure of lgn GL4/GALPHAI3 complex | x-ray diffraction | E, F, G, Z | — | — |
| 4G5S | Structure of LGN GL3/Galphai3 complex | x-ray diffraction | E, G, Z, F | — | — |
| 4G5S | Structure of lgn GL3/GALPHAI3 complex | x-ray diffraction | E, G, Z, F | — | — |
| 4JHR | An auto-inhibited conformation of LGN reveals a distinct interaction mode between GoLoco motifs and… | x-ray diffraction | A, B | — | — |
| 4JHR | An auto-inhibited conformation of lgn reveals a distinct interaction mode between goloco motifs and… | x-ray diffraction | A, B | — | — |
| 7EP7 | The complex structure of Gpsm2 and Whirlin | x-ray diffraction | A | — | 4 (best 0.44) |
| 7EP7 | The complex structure of GPSM2 and whirlin | x-ray diffraction | A | — | — |
| Q8VDU0 | AlphaFold monomer V2.0 prediction for G-protein-signaling modulator 2 (Q8VDU0) | predicted | A | — | — |
Experiment against prediction
- 4G2V chain A against the predicted model Q8VDU0: TM-score 0.98, RMSD 1.15 Å
- 4G2V chain A against the predicted model Q8VDU0: TM-score 0.98, RMSD 1.15 Å
- 3RO3 chain A against the predicted model Q8VDU0: TM-score 0.98, RMSD 0.69 Å
- 3RO3 chain A against the predicted model Q8VDU0: TM-score 0.98, RMSD 0.69 Å
- 3RO2 chain A against the predicted model Q8VDU0: TM-score 0.97, RMSD 1.51 Å
- 3RO2 chain A against the predicted model Q8VDU0: TM-score 0.97, RMSD 1.51 Å
- 7EP7 chain A against the predicted model Q8VDU0: TM-score 0.96, RMSD 1.59 Å
- 7EP7 chain A against the predicted model Q8VDU0: TM-score 0.96, RMSD 1.59 Å
- 4JHR chain B against the predicted model Q8VDU0: TM-score 0.88, RMSD 2.71 Å
- 4JHR chain B against the predicted model Q8VDU0: TM-score 0.88, RMSD 2.71 Å
Elsewhere
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