UniProt Q8VCD5
Mediator of RNA polymerase II transcription subunit 17 (Q8VCD5)
Mediator of RNA polymerase II transcription subunit 17 (UniProt Q8VCD5): 4 experimental structures and 1 predicted model on GenesisL1, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8VCD5
- Protein
- Mediator of RNA polymerase II transcription subunit 17
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 17 · 3 records with a druggable one
Structures
5 records of Q8VCD5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6W1S | Atomic model of the mammalian Mediator complex | electron microscopy | L | — | 7 (best 0.83) |
| 6W1S | Atomic model of the mammalian mediator complex | electron microscopy | L | — | — |
| 8T1I | Atomic model of the mammalian Mediator complex with MED26 subunit | electron microscopy | L | — | 4 (best 0.86) |
| 8T1L | Atomic model of the mammalian mouse Mediator complex with CKM module | electron microscopy | L | — | 6 (best 0.88) |
| Q8VCD5 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 17… | predicted | A | — | — |
Experiment against prediction
- 6W1S chain L against the predicted model Q8VCD5: TM-score 0.75, RMSD 3.66 Å
- 6W1S chain L against the predicted model Q8VCD5: TM-score 0.75, RMSD 3.66 Å
- 8T1L chain L against the predicted model Q8VCD5: TM-score 0.73, RMSD 3.59 Å
- 8T1I chain L against the predicted model Q8VCD5: TM-score 0.72, RMSD 3.74 Å
Elsewhere
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