UniProt Q8UB77
Probable 5-dehydro-4-deoxyglucarate dehydratase (Q8UB77)
Probable 5-dehydro-4-deoxyglucarate dehydratase (UniProt Q8UB77), EC 4.2.1.41: 10 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 35 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q8UB77
- Protein
- Probable 5-dehydro-4-deoxyglucarate dehydratase
- EC
- 4.2.1.41
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 35 · 4 records with a druggable one
Structures
11 records of Q8UB77 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4UR7 | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with pyruvate | x-ray diffraction | A, B, C, D | — | — |
| 4UR7 | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with pyruvate | x-ray diffraction | A, B, C, D | — | — |
| 4UR8 | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with 2-oxoadipic acid | x-ray diffraction | A, B, C, D | — | — |
| 4UR8 | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with 2-oxoadipic acid | x-ray diffraction | A, B, C, D | — | — |
| 5HWJ | Crystal structure of keto-deoxy-D-galactarate dehydratase | x-ray diffraction | A, B, C, D | — | 11 (best 0.67) |
| 5HWJ | Crystal structure of keto-deoxy-D-galactarate dehydratase | x-ray diffraction | A, B, C, D | — | — |
| 5HWM | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with 2-oxoadipic acid | x-ray diffraction | A, B, C, D | OOG | 11 (best 0.65) |
| 5HWM | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with 2-oxoadipic acid | x-ray diffraction | A, B, C, D | — | — |
| 5HWN | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with pyruvate | x-ray diffraction | A, B, C, D | PYR | 12 (best 0.67) |
| 5HWN | Crystal structure of keto-deoxy-D-galactarate dehydratase complexed with pyruvate | x-ray diffraction | A, B, C, D | — | — |
| Q8UB77 | AlphaFold monomer V2.0 prediction for probable 5-dehydro-4-deoxyglucarate dehydratase (Q8UB77) | predicted | A | — | 1 (best 0.57) |
Ligands
Experiment against prediction
- 4UR7 chain C against the predicted model Q8UB77: TM-score 0.99, RMSD 0.18 Å
- 4UR7 chain C against the predicted model Q8UB77: TM-score 0.99, RMSD 0.18 Å
- 5HWN chain C against the predicted model Q8UB77: TM-score 0.99, RMSD 0.19 Å
- 5HWN chain C against the predicted model Q8UB77: TM-score 0.99, RMSD 0.19 Å
- 5HWJ chain D against the predicted model Q8UB77: TM-score 0.99, RMSD 0.22 Å
- 5HWJ chain D against the predicted model Q8UB77: TM-score 0.99, RMSD 0.22 Å
- 5HWN chain D against the predicted model Q8UB77: TM-score 1.00, RMSD 0.23 Å
- 5HWN chain D against the predicted model Q8UB77: TM-score 1.00, RMSD 0.23 Å
- 4UR7 chain D against the predicted model Q8UB77: TM-score 1.00, RMSD 0.23 Å
- 4UR7 chain D against the predicted model Q8UB77: TM-score 1.00, RMSD 0.23 Å
Elsewhere
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