UniProt Q8U0R7
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase (Q8U0R7)
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase (UniProt Q8U0R7): 8 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q8U0R7
- Protein
- 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate…
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 3 · 1 record with a druggable one
Structures
9 records of Q8U0R7 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2R84 | Crystal structure of PurP from Pyrococcus furiosus complexed with AMP and AICAR | x-ray diffraction | A, B | — | — |
| 2R84 | Crystal structure of purp from pyrococcus furiosus complexed with AMP and aicar | x-ray diffraction | A, B | — | — |
| 2R85 | Crystal structure of PurP from Pyrococcus furiosus complexed with AMP | x-ray diffraction | A, B | — | — |
| 2R85 | Crystal structure of purp from pyrococcus furiosus complexed with AMP | x-ray diffraction | A, B | — | — |
| 2R86 | Crystal structure of PurP from Pyrococcus furiosus complexed with ATP | x-ray diffraction | A, B | — | — |
| 2R86 | Crystal structure of purp from pyrococcus furiosus complexed with ATP | x-ray diffraction | A, B | — | — |
| 2R87 | Crystal structure of PurP from Pyrococcus furiosus complexed with ADP | x-ray diffraction | A, B, C, D, E, F | — | — |
| 2R87 | Crystal structure of purp from pyrococcus furiosus complexed with ADP | x-ray diffraction | A, B, C, D, E, F | — | — |
| Q8U0R7 | AlphaFold monomer V2.0 prediction for 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl… | predicted | A | — | 3 (best 0.72) |
Experiment against prediction
- 2R87 chain A against the predicted model Q8U0R7: TM-score 0.98, RMSD 0.97 Å
- 2R87 chain A against the predicted model Q8U0R7: TM-score 0.98, RMSD 0.97 Å
- 2R84 chain B against the predicted model Q8U0R7: TM-score 0.95, RMSD 1.66 Å
- 2R84 chain B against the predicted model Q8U0R7: TM-score 0.95, RMSD 1.66 Å
- 2R86 chain B against the predicted model Q8U0R7: TM-score 0.94, RMSD 1.61 Å
- 2R86 chain B against the predicted model Q8U0R7: TM-score 0.94, RMSD 1.61 Å
- 2R85 chain B against the predicted model Q8U0R7: TM-score 0.93, RMSD 1.85 Å
- 2R85 chain B against the predicted model Q8U0R7: TM-score 0.93, RMSD 1.85 Å
- 2R84 chain A against the predicted model Q8U0R7: TM-score 0.93, RMSD 2.00 Å
- 2R84 chain A against the predicted model Q8U0R7: TM-score 0.93, RMSD 2.00 Å
Elsewhere
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