UniProt Q8U0E8
DNA-directed RNA polymerase subunit Rpo6 (Q8U0E8)
DNA-directed RNA polymerase subunit Rpo6 (UniProt Q8U0E8), EC 2.7.7.6: 5 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8U0E8
- Protein
- DNA-directed RNA polymerase subunit Rpo6
- EC
- 2.7.7.6
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 12 · 5 records with a druggable one
Structures
6 records of Q8U0E8 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8CRO | Cryo-EM structure of Pyrococcus furiosus transcription elongation complex | electron microscopy | K | — | 2 (best 0.70) |
| 8OKI | Cryo-EM structure of Pyrococcus furiosus transcription elongation complex bound to Spt4/5 | electron microscopy | K | — | 2 (best 0.72) |
| 8ORQ | Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase open clamp conformation | electron microscopy | K | — | 3 (best 0.68) |
| 8P2I | Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation with… | electron microscopy | K | — | 2 (best 0.72) |
| 8RBO | Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation | electron microscopy | K | — | 3 (best 0.70) |
| Q8U0E8 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit K (Q8U0E8) | predicted | A | — | — |
Experiment against prediction
- 8CRO chain K against the predicted model Q8U0E8: TM-score 0.96, RMSD 0.54 Å
- 8P2I chain K against the predicted model Q8U0E8: TM-score 0.95, RMSD 0.60 Å
- 8OKI chain K against the predicted model Q8U0E8: TM-score 0.94, RMSD 0.61 Å
- 8ORQ chain K against the predicted model Q8U0E8: TM-score 0.94, RMSD 0.68 Å
- 8RBO chain K against the predicted model Q8U0E8: TM-score 0.93, RMSD 0.87 Å
Elsewhere
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