UniProt Q8TZK1
Transcription elongation factor Spt5 (Q8TZK1)
Transcription elongation factor Spt5 (UniProt Q8TZK1): 6 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8TZK1
- Protein
- Transcription elongation factor Spt5
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
7 records of Q8TZK1 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3P8B | X-ray crystal structure of Pyrococcus furiosus transcription elongation factor Spt4/5 | x-ray diffraction | B, D | — | — |
| 3P8B | X-ray crystal structure of pyrococcus furiosus transcription elongation factor SPT4/5 | x-ray diffraction | B, D | — | — |
| 3QQC | Crystal structure of archaeal Spt4/5 bound to the RNAP clamp domain | x-ray diffraction | D | — | — |
| 3QQC | Crystal structure of archaeal SPT4/5 bound to the rnap clamp domain | x-ray diffraction | D | — | — |
| 8OKI | Cryo-EM structure of Pyrococcus furiosus transcription elongation complex bound to Spt4/5 | electron microscopy | G | — | 2 (best 0.67) |
| 8P2I | Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation with… | electron microscopy | G | — | — |
| Q8TZK1 | AlphaFold monomer V2.0 prediction for transcription elongation factor SPT5 (Q8TZK1) | predicted | A | — | — |
Experiment against prediction
- 8P2I chain G against the predicted model Q8TZK1: TM-score 0.94, RMSD 0.86 Å
- 3QQC chain D against the predicted model Q8TZK1: TM-score 0.94, RMSD 1.06 Å
- 3QQC chain D against the predicted model Q8TZK1: TM-score 0.94, RMSD 1.06 Å
- 8OKI chain G against the predicted model Q8TZK1: TM-score 0.93, RMSD 1.00 Å
- 3P8B chain B against the predicted model Q8TZK1: TM-score 0.60, RMSD 2.45 Å
- 3P8B chain B against the predicted model Q8TZK1: TM-score 0.60, RMSD 2.45 Å
Elsewhere
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