UniProt Q8TF46
DIS3-like exonuclease 1 (Q8TF46)
DIS3-like exonuclease 1 (UniProt Q8TF46), EC 3.1.13.1: 4 experimental structures and 1 predicted model on GenesisL1, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8TF46
- Protein
- DIS3-like exonuclease 1
- EC
- 3.1.13.1
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 18 · 4 records with a druggable one
Structures
5 records of Q8TF46 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 9G8M | human 80S ribosome bound by a SKI2-exosome complex | electron microscopy | M | — | 1 (best 0.87) |
| 9G8N | 80S-bound human Ski2-exosome complex | electron microscopy | M | — | 8 (best 0.84) |
| 9G8O | human 40S ribosome bound by a SKI238-exosome complex | electron microscopy | M | — | 2 (best 0.87) |
| 9G8P | 40S-bound human SKI2-exosome complex | electron microscopy | M | — | 7 (best 0.86) |
| Q8TF46 | AlphaFold monomer V2.0 prediction for DIS3-like exonuclease 1 (Q8TF46) | predicted | A | — | — |
Experiment against prediction
- 9G8M chain M against the predicted model Q8TF46: TM-score 0.71, RMSD 2.57 Å
- 9G8N chain M against the predicted model Q8TF46: TM-score 0.70, RMSD 2.54 Å
- 9G8P chain M against the predicted model Q8TF46: TM-score 0.70, RMSD 2.56 Å
- 9G8O chain M against the predicted model Q8TF46: TM-score 0.70, RMSD 2.59 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.