UniProt Q8TDU9
Relaxin-3 receptor 2 (Q8TDU9)
Relaxin-3 receptor 2 (UniProt Q8TDU9): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8TDU9
- Protein
- Relaxin-3 receptor 2
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 16 · 4 records with a druggable one
Structures
4 records of Q8TDU9 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7YJ4 | Cryo-EM structure of the INSL5-bound human relaxin family peptidereceptor 4 (RXFP4)-Gi complex | electron microscopy | R | — | 5 (best 0.78) |
| 7YK6 | Cryo-EM structure of the compound 4-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex | electron microscopy | R | IYF | 4 (best 0.79) |
| 7YK7 | Cryo-EM structure of the DC591053-bound human relaxin family peptide receptor 4 (RXFP4)-Gi complex | electron microscopy | R | IYM | 5 (best 0.80) |
| Q8TDU9 | AlphaFold monomer V2.0 prediction for relaxin-3 receptor 2 (Q8TDU9) | predicted | A | — | 2 (best 0.76) |
Ligands
Experiment against prediction
- 7YK7 chain R against the predicted model Q8TDU9: TM-score 0.94, RMSD 1.74 Å
- 7YK6 chain R against the predicted model Q8TDU9: TM-score 0.93, RMSD 1.89 Å
- 7YJ4 chain R against the predicted model Q8TDU9: TM-score 0.93, RMSD 1.89 Å
Elsewhere
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