UniProt Q8TDN6
Ribosome biogenesis protein BRX1 homolog (Q8TDN6)
Ribosome biogenesis protein BRX1 homolog (UniProt Q8TDN6): 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8TDN6
- Protein
- Ribosome biogenesis protein BRX1 homolog
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 9 records with a druggable one
Structures
11 records of Q8TDN6 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FKP | Human nucleolar pre-60S ribosomal subunit (State A1) | electron microscopy | SO | MG | — |
| 8FKQ | Human nucleolar pre-60S ribosomal subunit (State A2) | electron microscopy | SO | MG | 2 (best 0.89) |
| 8FKR | Human nucleolar pre-60S ribosomal subunit (State B1) | electron microscopy | SO | MG | 2 (best 0.87) |
| 8FKS | Human nucleolar pre-60S ribosomal subunit (State B2) | electron microscopy | SO | MG | 1 (best 0.87) |
| 8FKT | Human nucleolar pre-60S ribosomal subunit (State C1) | electron microscopy | SO | MG | 2 (best 0.87) |
| 8FKU | Human nucleolar pre-60S ribosomal subunit (State C2) | electron microscopy | SO | MG | 1 (best 0.89) |
| 8FKV | Human nucleolar pre-60S ribosomal subunit (State D1) | electron microscopy | SO | MG | 3 (best 0.89) |
| 8FKW | Human nucleolar pre-60S ribosomal subunit (State D2) | electron microscopy | SO | MG | 3 (best 0.88) |
| 8FKX | Human nucleolar pre-60S ribosomal subunit (State E) | electron microscopy | SO | MG | 2 (best 0.88) |
| 8FKY | Human nucleolar pre-60S ribosomal subunit (State F) | electron microscopy | SO | MG | 2 (best 0.88) |
| Q8TDN6 | AlphaFold monomer V2.0 prediction for ribosome biogenesis protein BRX1 homolog (Q8TDN6) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 10 records
Experiment against prediction
- 8FKY chain SO against the predicted model Q8TDN6: TM-score 0.75, RMSD 2.93 Å
- 8FKX chain SO against the predicted model Q8TDN6: TM-score 0.75, RMSD 2.92 Å
- 8FKW chain SO against the predicted model Q8TDN6: TM-score 0.75, RMSD 2.98 Å
- 8FKU chain SO against the predicted model Q8TDN6: TM-score 0.74, RMSD 2.94 Å
- 8FKS chain SO against the predicted model Q8TDN6: TM-score 0.74, RMSD 2.96 Å
- 8FKQ chain SO against the predicted model Q8TDN6: TM-score 0.74, RMSD 2.95 Å
- 8FKV chain SO against the predicted model Q8TDN6: TM-score 0.72, RMSD 2.95 Å
- 8FKP chain SO against the predicted model Q8TDN6: TM-score 0.72, RMSD 2.96 Å
- 8FKT chain SO against the predicted model Q8TDN6: TM-score 0.72, RMSD 2.94 Å
- 8FKR chain SO against the predicted model Q8TDN6: TM-score 0.72, RMSD 2.94 Å
Elsewhere
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