UniProt Q8TDD1
ATP-dependent RNA helicase DDX54 (Q8TDD1)
ATP-dependent RNA helicase DDX54 (UniProt Q8TDD1), EC 3.6.4.13: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8TDD1
- Protein
- ATP-dependent RNA helicase DDX54
- EC
- 3.6.4.13
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 12 · 6 records with a druggable one
Structures
7 records of Q8TDD1 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FKT | Human nucleolar pre-60S ribosomal subunit (State C1) | electron microscopy | NI | ADP | 2 (best 0.87) |
| 8FKU | Human nucleolar pre-60S ribosomal subunit (State C2) | electron microscopy | NI | ADP | 1 (best 0.87) |
| 8FKV | Human nucleolar pre-60S ribosomal subunit (State D1) | electron microscopy | NI | ADP, MG | 2 (best 0.86) |
| 8FKW | Human nucleolar pre-60S ribosomal subunit (State D2) | electron microscopy | NI | ADP, MG | 3 (best 0.87) |
| 8FKX | Human nucleolar pre-60S ribosomal subunit (State E) | electron microscopy | NI | ADP, MG | 2 (best 0.86) |
| 8FKY | Human nucleolar pre-60S ribosomal subunit (State F) | electron microscopy | NI | ADP, MG | 2 (best 0.87) |
| Q8TDD1 | AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DDX54 (Q8TDD1) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8FKU chain NI against the predicted model Q8TDD1: TM-score 0.78, RMSD 4.71 Å
- 8FKT chain NI against the predicted model Q8TDD1: TM-score 0.78, RMSD 4.72 Å
- 8FKY chain NI against the predicted model Q8TDD1: TM-score 0.77, RMSD 4.68 Å
- 8FKX chain NI against the predicted model Q8TDD1: TM-score 0.77, RMSD 4.68 Å
- 8FKW chain NI against the predicted model Q8TDD1: TM-score 0.74, RMSD 4.92 Å
- 8FKV chain NI against the predicted model Q8TDD1: TM-score 0.74, RMSD 4.94 Å
Elsewhere
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