UniProt Q8TDB6
E3 ubiquitin-protein ligase DTX3L (Q8TDB6)
E3 ubiquitin-protein ligase DTX3L (UniProt Q8TDB6), EC 2.3.2.27: 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8TDB6
- Protein
- E3 ubiquitin-protein ligase DTX3L
- EC
- 2.3.2.27
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
4 records of Q8TDB6 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3PG6 | The carboxyl terminal domain of human deltex 3-like | x-ray diffraction | A, B, C, D | — | — |
| 3PG6 | The carboxyl terminal domain of human deltex 3-like | x-ray diffraction | A, B, C, D | — | — |
| 8R79 | The D2 domain of human DTX3L | x-ray diffraction | A, B, C, D | SO4 | 1 (best 0.70) |
| Q8TDB6 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase DTX3L (Q8TDB6) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 3PG6 chain D against the predicted model Q8TDB6: TM-score 0.99, RMSD 0.52 Å
- 3PG6 chain D against the predicted model Q8TDB6: TM-score 0.99, RMSD 0.52 Å
- 3PG6 chain B against the predicted model Q8TDB6: TM-score 0.98, RMSD 0.55 Å
- 3PG6 chain B against the predicted model Q8TDB6: TM-score 0.98, RMSD 0.55 Å
- 3PG6 chain C against the predicted model Q8TDB6: TM-score 0.98, RMSD 0.56 Å
- 3PG6 chain C against the predicted model Q8TDB6: TM-score 0.98, RMSD 0.56 Å
- 3PG6 chain A against the predicted model Q8TDB6: TM-score 0.98, RMSD 0.68 Å
- 3PG6 chain A against the predicted model Q8TDB6: TM-score 0.98, RMSD 0.68 Å
- 8R79 chain B against the predicted model Q8TDB6: TM-score 0.92, RMSD 0.91 Å
- 8R79 chain D against the predicted model Q8TDB6: TM-score 0.92, RMSD 0.98 Å
Elsewhere
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