UniProt Q8TCX1
Cytoplasmic dynein 2 light intermediate chain 1 (Q8TCX1)
Cytoplasmic dynein 2 light intermediate chain 1 (UniProt Q8TCX1): 5 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8TCX1
- Protein
- Cytoplasmic dynein 2 light intermediate chain 1
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 9 · 3 records with a druggable one
Structures
6 records of Q8TCX1 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6RLB | Structure of the dynein-2 complex; tail domain | electron microscopy | E, F | — | 5 (best 0.77) |
| 6RLB | Structure of the dynein-2 complex; tail domain | electron microscopy | E, F | — | — |
| 6SC2 | Structure of the dynein-2 complex; IFT-train bound model | electron microscopy | E, F | — | 2 (best 0.75) |
| 6SC2 | Structure of the dynein-2 complex; ift-train bound model | electron microscopy | E, F | — | — |
| 8RGH | Structure of dynein-2 intermediate chain DYNC2I1 (WDR60) in complex with the dynein-2 heavy chain… | electron microscopy | E | — | 2 (best 0.84) |
| Q8TCX1 | AlphaFold monomer V2.0 prediction for cytoplasmic dynein 2 light intermediate chain 1 (Q8TCX1) | predicted | A | — | — |
Experiment against prediction
- 6SC2 chain E against the predicted model Q8TCX1: TM-score 0.79, RMSD 2.89 Å
- 6SC2 chain E against the predicted model Q8TCX1: TM-score 0.79, RMSD 2.89 Å
- 6RLB chain E against the predicted model Q8TCX1: TM-score 0.79, RMSD 2.89 Å
- 6RLB chain E against the predicted model Q8TCX1: TM-score 0.79, RMSD 2.89 Å
- 6RLB chain F against the predicted model Q8TCX1: TM-score 0.78, RMSD 3.00 Å
- 6RLB chain F against the predicted model Q8TCX1: TM-score 0.78, RMSD 3.00 Å
- 6SC2 chain F against the predicted model Q8TCX1: TM-score 0.78, RMSD 3.00 Å
- 6SC2 chain F against the predicted model Q8TCX1: TM-score 0.78, RMSD 3.00 Å
- 8RGH chain E against the predicted model Q8TCX1: TM-score 0.70, RMSD 0.97 Å
Elsewhere
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