UniProt Q8TCG2
Phosphatidylinositol 4-kinase type 2-beta (Q8TCG2)
Phosphatidylinositol 4-kinase type 2-beta (UniProt Q8TCG2), EC 2.7.1.67, 3.2.1.17: 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 11 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q8TCG2
- Protein
- Phosphatidylinositol 4-kinase type 2-beta
- EC
- 2.7.1.67, 3.2.1.17
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 11 · 2 records with a druggable one
Structures
4 records of Q8TCG2 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4WTV | Crystal structure of the phosphatidylinositol 4-kinase IIbeta | x-ray diffraction | A, B | — | — |
| 4WTV | Crystal structure of the phosphatidylinositol 4-kinase iibeta | x-ray diffraction | A, B | — | — |
| 8A5X | Crystal structure of phosphatidyl inositol 4-kinase II beta in complex with MM1373 | x-ray diffraction | A | L6A | 2 (best 0.81) |
| Q8TCG2 | AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-kinase type 2-beta (Q8TCG2) | predicted | A | — | 9 (best 0.71) |
Ligands
- L6A · 4-azanyl-7-[3-(hydroxymethyl)phenyl]quinazoline-6-carboxamide · in 1 record
Experiment against prediction
- 4WTV chain B against the predicted model Q8TCG2: TM-score 0.68, RMSD 1.34 Å
- 4WTV chain B against the predicted model Q8TCG2: TM-score 0.68, RMSD 1.34 Å
- 8A5X chain A against the predicted model Q8TCG2: TM-score 0.65, RMSD 1.68 Å
- 4WTV chain A against the predicted model Q8TCG2: TM-score 0.62, RMSD 1.40 Å
- 4WTV chain A against the predicted model Q8TCG2: TM-score 0.62, RMSD 1.40 Å
Elsewhere
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