UniProt Q8TB36
Ganglioside-induced differentiation-associated protein 1 (Q8TB36)
Ganglioside-induced differentiation-associated protein 1 (UniProt Q8TB36): 13 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 51 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q8TB36
- Protein
- Ganglioside-induced differentiation-associated protein 1
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 51 · 7 records with a druggable one
Structures
14 records of Q8TB36 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7AIA | Complex of human GDAP1 with hexadecanedioic acid | x-ray diffraction | AAA, BBB | RF8 | 6 (best 0.67) |
| 7ALM | Crystal structure of human GDAP1 at 2.8 Angstrom resolution. | x-ray diffraction | A, B | — | 5 (best 0.61) |
| 7ALM | Crystal structure of human GDAP1 at 2.8 ångström resolution. | x-ray diffraction | A, B | — | — |
| 7B2G | Crystal structure of R120Q GDAP1 mutant | x-ray diffraction | A | — | 5 (best 0.47) |
| 7B2G | Crystal structure of R120Q GDAP1 mutant | x-ray diffraction | A | — | — |
| 7Q6J | Crystal structure of the human GDAP1 CMT2 mutant-H123R | x-ray diffraction | A, B | — | 8 (best 0.62) |
| 7Q6J | Crystal structure of the human GDAP1 CMT2 mutant-H123R | x-ray diffraction | A, B | — | — |
| 7Q6K | Crystal structure of the human GDAP1 CMT2 mutant-R120W | x-ray diffraction | A | — | 3 (best 0.54) |
| 7Q6K | Crystal structure of the human GDAP1 CMT2 mutant-R120W | x-ray diffraction | A | — | — |
| 7YWD | Human GDAP1 core domain, trigonal crystal form | x-ray diffraction | A, B, C, D | — | 14 (best 0.80) |
| 7YWD | Human GDAP1 core domain, trigonal crystal form | x-ray diffraction | A, B, C, D | — | — |
| 8A4J | Human GDAP1, A247V mutant | x-ray diffraction | A, B | — | 6 (best 0.61) |
| 8A4K | Human GDAP1, R282H mutant | x-ray diffraction | A, B | — | 4 (best 0.58) |
| Q8TB36 | AlphaFold monomer V2.0 prediction for ganglioside-induced differentiation-associated protein 1… | predicted | A | — | — |
Ligands
- RF8 · hexadecanedioic acid · in 1 record
Experiment against prediction
- 8A4K chain B against the predicted model Q8TB36: TM-score 0.90, RMSD 1.85 Å
- 8A4J chain B against the predicted model Q8TB36: TM-score 0.90, RMSD 1.90 Å
- 7ALM chain B against the predicted model Q8TB36: TM-score 0.90, RMSD 1.79 Å
- 7ALM chain B against the predicted model Q8TB36: TM-score 0.90, RMSD 1.79 Å
- 7Q6K chain A against the predicted model Q8TB36: TM-score 0.89, RMSD 1.97 Å
- 7Q6K chain A against the predicted model Q8TB36: TM-score 0.89, RMSD 1.97 Å
- 7Q6J chain B against the predicted model Q8TB36: TM-score 0.89, RMSD 1.96 Å
- 7Q6J chain B against the predicted model Q8TB36: TM-score 0.89, RMSD 1.96 Å
- 7AIA chain BBB against the predicted model Q8TB36: TM-score 0.89, RMSD 2.03 Å
- 7B2G chain A against the predicted model Q8TB36: TM-score 0.89, RMSD 2.03 Å
Elsewhere
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