UniProt Q8RXG3
Mitogen-activated protein kinase kinase 5 (Q8RXG3)
Mitogen-activated protein kinase kinase 5 (UniProt Q8RXG3), EC 2.7.12.2: 1 experimental structure and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8RXG3
- Protein
- Mitogen-activated protein kinase kinase 5
- EC
- 2.7.12.2
- Experimental structures
- 1
- Predicted models
- 1
- Pockets
- 22 · 2 records with a druggable one
Structures
2 records of Q8RXG3 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7XBR | Crystal structure of phosphorylated AtMKK5 | x-ray diffraction | A, B, C, D, E, F, G, H | — | 20 (best 0.65) |
| Q8RXG3 | AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase kinase 5 (Q8RXG3) | predicted | A | — | 2 (best 0.77) |
Experiment against prediction
- 7XBR chain B against the predicted model Q8RXG3: TM-score 0.90, RMSD 1.78 Å
- 7XBR chain A against the predicted model Q8RXG3: TM-score 0.90, RMSD 1.83 Å
- 7XBR chain D against the predicted model Q8RXG3: TM-score 0.90, RMSD 1.78 Å
- 7XBR chain H against the predicted model Q8RXG3: TM-score 0.90, RMSD 1.81 Å
- 7XBR chain G against the predicted model Q8RXG3: TM-score 0.90, RMSD 1.80 Å
- 7XBR chain F against the predicted model Q8RXG3: TM-score 0.90, RMSD 1.82 Å
- 7XBR chain C against the predicted model Q8RXG3: TM-score 0.90, RMSD 1.89 Å
Elsewhere
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