UniProt Q8RSQ2
Barbiturase (Q8RSQ2)
Barbiturase (UniProt Q8RSQ2), EC 3.5.2.1: 8 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8RSQ2
- Protein
- Barbiturase
- EC
- 3.5.2.1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 15 · 1 record with a druggable one
Structures
9 records of Q8RSQ2 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5HWE | high resolution structure of barbiturase | x-ray diffraction | A | MG, SO4, MHA | — |
| 5HWE | High resolution structure of barbiturase | x-ray diffraction | A | — | — |
| 5HXU | Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of… | x-ray diffraction | A, B | SO4, MHA, NA, CL | — |
| 5HXU | Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of… | x-ray diffraction | A, B | — | — |
| 5HXZ | Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of… | x-ray diffraction | A, B, C, D | CL, MHA, NA | 15 (best 0.89) |
| 5HXZ | Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of… | x-ray diffraction | A, B, C, D | — | — |
| 5HY1 | high resolution structure of barbiturase | x-ray diffraction | A | WDL, NA, CL | — |
| 5HY1 | High resolution structure of barbiturase | x-ray diffraction | A | — | — |
| Q8RSQ2 | AlphaFold monomer V2.0 prediction for barbiturase (Q8RSQ2) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5HY1 chain A against the predicted model Q8RSQ2: TM-score 1.00, RMSD 0.29 Å
- 5HY1 chain A against the predicted model Q8RSQ2: TM-score 1.00, RMSD 0.29 Å
- 5HWE chain A against the predicted model Q8RSQ2: TM-score 0.99, RMSD 0.34 Å
- 5HWE chain A against the predicted model Q8RSQ2: TM-score 0.99, RMSD 0.34 Å
- 5HXZ chain A against the predicted model Q8RSQ2: TM-score 1.00, RMSD 0.43 Å
- 5HXZ chain A against the predicted model Q8RSQ2: TM-score 1.00, RMSD 0.43 Å
- 5HXU chain A against the predicted model Q8RSQ2: TM-score 0.99, RMSD 0.60 Å
- 5HXU chain A against the predicted model Q8RSQ2: TM-score 0.99, RMSD 0.60 Å
- 5HXZ chain B against the predicted model Q8RSQ2: TM-score 0.99, RMSD 0.75 Å
- 5HXZ chain B against the predicted model Q8RSQ2: TM-score 0.99, RMSD 0.75 Å
Elsewhere
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